Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-29T07:30:21.018Z Has data issue: false hasContentIssue false

A polymer-based Chronic Nerve Interface Microelectrode Array

Published online by Cambridge University Press:  01 February 2011

Brian Farrell
Affiliation:
[email protected], Foster-Miller, Inc., Materials Technology, 195 Bear Hill Road, Waltham, MA, 02451, United States, 781-684-4150
Linas Jauniskis
Affiliation:
[email protected], Foster-Miller, Inc., Materials Technology, 195 Bear Hill Road, Waltham, MA, 02451, United States
Thomas Phely-Bobin
Affiliation:
[email protected], Foster-Miller, Inc., Materials Technology, 195 Bear Hill Road, Waltham, MA, 02451, United States
Richard Streeter
Affiliation:
[email protected], Foster-Miller, Inc., Materials Technology, 195 Bear Hill Road, Waltham, MA, 02451, United States
David Edell
Affiliation:
[email protected], InnerSea Technology, 1 DeAngelo Drive, Bedford, MA, 01730, United States
Robert Dean
Affiliation:
[email protected], Auburn University, 200 Broun Hall, Auburn, AL, 36830, United States
Get access

Abstract

This paper will present ongoing work in the development of a thin, flexible, photolithographically-defined polymer-based electrode array based on Liquid Crystal Polymer (LCP) films and substrates. The goal of the effort is to develop and qualify a new platform technology that would allow accurate positioning of large numbers of electrode contacts in neural tissue for chronic applications. LCP films are a far greater match to the density of neural tissue than the competing wire and silicon arrays and thus will match the bending and flexing as the neural tissues change dimension. This flexibility would cause less neural damage and will maintain a more constant relationship with local neurons. Technology development activities include thin film metallization, interconnect insulation and device microfabrication.

Type
Research Article
Copyright
Copyright © Materials Research Society 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Hetke, J. F. and Anderson, D. J., “Silicon microelectrodes for extracellular recording,” Handbook of Neuroprosthetic Methods, Finn, W. E. and LoPresti, P. G., Eds. Boca Raton, FL: CRC Press, 2002.Google Scholar
2. Wise, K. D., Anderson, D. J., Hetke, J. F., Kipke, D. R., and Najafi, K., “Wireless implantable microsystems: High-density electronic interfaces to the nervous system,” Proceedings of the IEEE, vol. 92, pp. 7697, 2004.Google Scholar
3. Vetter, R. J., Williams, J. C., Hetke, J. F., Nunamaker, E. A., and Kipke, D. R., “Chronic neural recording using silicon-substrate microelectrode arrays implanted in cerebral cortex.,” IEEE Transactions On Biomedical Engineering, vol. 51, pp. 896904, 2004.Google Scholar
4. Hetke, J. F., Lund, J. L., Najafi, K., Wise, K. D., and Anderson, D. J., “Silicon ribbon cables for chronically implantable microelectrode arrays,” IEEE Trans Biomed Eng, vol. 41, pp. 314–21, 1994.Google Scholar
5. Edell, D. and Gleason, K., Insulating Biomaterials NIH Contract #NO1-NS-9-2323. 1999, InnerSea Technology: Bedford.Google Scholar
6.NIH Grant # 1R43HL61122-01, Long life compliance chambers for artificial heart implants Google Scholar
7. Farrell, B., Jaynes, P., Johnson, W. and Dean, R., ‘The Liquid Crystal Polymer Packaging Solution’, International Microelectronics and Packaging Society Annual Conference, Nov. 17-20, 2003, Boston.Google Scholar
8. Haugsjaa, P., Lusignea, R., Kasturi, S., Farrell, B. and Bowman, A.; ‘Progress Towards Optoelectronic MCMs for Parallel Interconnection’, IMAPS MCM Applications Workshop, June 2000, Newport, Rhode Island Google Scholar
9. Jayaraj, K. and Farrell, B.; ‘Liquid Crystal Polymers and their Role in Electronic Packaging’; Advancing Microelectronics, Volume 25, No. 4. 10. B. Farrell and K. Jayaraj; ‘Low Cost, Thermally Efficient 3-D MCMs’; DARPA EP&I Conference, March 1997, San Diego, CaliforniaGoogle Scholar
11. Jayaraj, K., Felton, L. and Farrell, B.; ‘Low Cost, Multichip Modules Based on Liquid Crystal Polymers’; 16th Digital Avionics Systems Conference, 1997, Irvine, California.Google Scholar
12. Jayaraj, K., Felton, L., Tiano, T. and Farrell, B.; ‘The Preliminary Development of a Novel Corrosion Resistant Plastic Package’ InterPACK ’97, Hawaii.Google Scholar
13.NIH Grant #: 1R43NS41117-01, ‘Microribbon cable for implantable microelectronicsGoogle Scholar
14.NIH Grant #: 1R43NS046106-01, ‘A polymer-based, chronic neurotrophic electrode array Google Scholar