Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-27T02:42:47.797Z Has data issue: false hasContentIssue false

Patterned Sol-Gel Structures by Micro Molding in Capillaries

Published online by Cambridge University Press:  15 February 2011

M. J. Lochhead
Affiliation:
Center for Bioengineering, University of Washington, Seattle, WA 98195, [email protected], [email protected]
P. Yager
Affiliation:
Center for Bioengineering, University of Washington, Seattle, WA 98195, [email protected], [email protected]
Get access

Abstract

The development of a variety of micro-optical chemical sensor and biosensor devices will rely on an ability to fabricate and effectively pattern physically and chemically sensitive materials. Toward this end, organically modified sol-gel materials are patterned onto a substrate using a benign technique called micro molding in capillaries (MIMIC). Closely spaced, organically modified silica ridges containing organic dyes are demonstrated. The mold consists of a micro channel-filled elastomeric master in contact with a glass substrate. Liquid sols fill the mold as a result of capillary action. A reservoir-channel system in the mold allows simultaneous casting of sols with different chemical compositions. After gelation, the elastomeric master is removed and sol-gel structures are left on the substrate. Cross-sectional dimensions of the ridges range from one to tens of micrometers, and can be centimeters in length. Because of the mild processing conditions, the method is especially attractive for solgel materials containing sensitive molecules such as indicator dyes and biomolecules. The technique holds promise for microfabricated sensor and integrated optics applications.

Type
Research Article
Copyright
Copyright © Materials Research Society 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Kovacs, G.T.A., Peterson, K., and Albin, M., Anal. Chem. 68, 407A (1996).Google Scholar
2. Better Ceramics Through Chemistry VII: Organic/Inorganic Hybrid Materials, edited by Coltrain, B.K., Sanchez, C., Schaefer, D.W., and Wilkes, G.L. (Mater. Res. Soc. Proc. 435, Pittsburgh, PA 1996).Google Scholar
3. Tsionsky, M., Rabinovich, L., Glezer, V., Sampath, S., Pankratov, I., and Gun, J., Anal. Chem. 67, 22A (1995).Google Scholar
4. Avnir, D., Braun, S., Lev, O., and Ottolenghi, M., Chem. Mater. 6, 1605 (1994).Google Scholar
5. Dave, B.C., Dunn, B., Valentine, J.S., and Zink, J. I., Anal. Chem. 66, 1120A (1994).Google Scholar
6. Krug, H. and Schmidt, H., New J. Chem. 18, 1125 (1994).Google Scholar
7. Li, C.Y., Chisham, J., Andrews, M., Najafi, S.I., Mackenzie, J.D., and Peyghambarian, N., Electronics Lett. 31, 271 (1995).Google Scholar
8. Holmes, A.S., Syms, R.R.A., Li, M., and Green, M., Appl. Opt. 32, 4916 (1993).Google Scholar
9. Mendoza, E. A., Ferrell, D.J., Syracuse, S.J., Khalil, A.N., and Lieberman, R.A., in Sol-Gel Optics III, edited by Mackenzie, J.D.. (SPIE Proc. Ser. 2288, Bellingham, WA 1994), p. 580.Google Scholar
10. Kim, E., Xia, Y., and Whitesides, G.M., Nature 376, 581 (1995).Google Scholar
11. Kim, E., Xia, Y., Whitesides, G.M., J. Am. Chem. Soc. 118, 5722 (1996).Google Scholar
12. Xia, Y., Kim, E., Zhao, X.-M., Rogers, J.A., Prentiss, M., Whitesides, G.M., Science 273, 347 (1996).Google Scholar
13. Xia, Y., Kim, E., Whitesides, G.M., Chem. Mater. 8, 1558 (1996).Google Scholar
14. Jeon, N.L., Clem, P.G., Nuzzo, R.G., Payne, D.A., J. Mater. Res. 10, 2996 (1995).Google Scholar
15. Motakef, S., Boulton, J.M., Roncone, R.L., Neilson, G., Teowee, G., and Uhlmann, D.R. Appl. Opt. 34, 721 (1995).Google Scholar
16. Brinker, C.J. and Scherer, G.W., Sol-Gel Science: The Physics and Chemistry of Sol-Gel Processing, Academic Press, Bostoin, 1990, p. 506.Google Scholar