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Oligonucleotide Metallization for Conductive Bio-Inorganic Interfaces in Self Assembled Nanoelectronics and Nanosystems

Published online by Cambridge University Press:  01 February 2011

Xu Wang ,
Krishna Singh ,
Chris Tsai ,
Roger Lake ,
Alexander Balandin  and
Mihri Ozkan
Xu Wang
Affiliation:
Chemical and Environmental Engineering Department
Krishna Singh
Affiliation:
Chemical and Environmental Engineering Department
Chris Tsai
Affiliation:
Electrical Engineering Department; Cengiz Ozkan, Mechanical Engineering Department; University of California, Riverside, 92521USA
Roger Lake
Affiliation:
Electrical Engineering Department; Cengiz Ozkan, Mechanical Engineering Department; University of California, Riverside, 92521USA
Alexander Balandin
Affiliation:
Electrical Engineering Department; Cengiz Ozkan, Mechanical Engineering Department; University of California, Riverside, 92521USA
Mihri Ozkan
Affiliation:
Electrical Engineering Department; Cengiz Ozkan, Mechanical Engineering Department; University of California, Riverside, 92521USA
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Abstract

Properly designed sequences of oligonucleotides can be employed as scaffolds or templates for the self-organization of nanostructures and devices, through the Watson-Crick base pairing mechanism which serves as a programmable smart glue. In this paper, we report the Platinum metallization of peptide nucleic acid (PNA) sequences for the first time. PNA is an analogue of DNA and has a neutral backbone which provides stronger hybridization, greater stability and higher specificity in base pairing. Pt ions were reduced from a salt solution and localized over the PNA fragments where the size of the Pt colloids depends on the duration of chemical reduction. Computations of the high lying occupied and lowlying unoccupied orbitals indicated that Pt nanoparticles bind easily on both the Thymine (T) bases and the backbone in the PNA.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 872: Symposium J – Micro- and Nanosystems—Materials and Devices , 2005 , J10.2
Copyright
Copyright © Materials Research Society 2005

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