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A Novel Method For Solution Deposition of Hydroxyapatite on to Three Dimensionally Porous Metallic Surfaces: Peri-Apatite Ha

Published online by Cambridge University Press:  10 February 2011

Joseph P. Zitelli  and
Paul Higham
Joseph P. Zitelli
Affiliation:
Stryker Howmedica Osteonics, Advanced Technology Group, Rutherford, New Jersey.
Paul Higham
Affiliation:
Stryker Howmedica Osteonics, Advanced Technology Group, Rutherford, New Jersey.
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Abstract

A method for applying HA coatings to metallic surfaces, without the use of high temperature plasma spraying, has been developed. The HA coating is precipitated in an aqueous solution under conditions similar to those occurring in the body during bone formation. This surface mineralization process results in a coating which is highly crystalline and 100% HA. Processing and characterization experimentation and results are included in the paper.

The coating method has the ability to penetrate macroporous (> 100 micron pores) metal structures and coat the undersides and interior surfaces of the areas designed for bone ingrowth on orthopedic devices used for joint replacements. This ability to coat all around a surface is the basis for the name Peri-Apatite HA. Electron microscopy is presented illustrating the coverage and morphology of the coating.

The Peri-Apatite HA coating is currently used on both knee joint replacement and hip joint replacement implants.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 599: Symposium DD – Mineralization in Natural & Synthetic Biomaterials , 1999 , 117
Copyright
Copyright © Materials Research Society 2000

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References

1. Geesink, R. G. T. and Hoefnagels, N. H. M., SIX-YEAR RESULTS OF HYDROXYAPATITE-COATED TOTAL HIP REPLACEMENT, J Bone Joint. Surg. [Br] 77–B:534–47 (1995).Google Scholar
2. Capello, W. N., D'Antonio, J. A., Manley, M. T., Feinberg, J.R.. HYDROXYAPATITE IN TOTAL HIP ARTHROPLAST Y. CLINICAL RESULTS AND CRITICAL ISSUE S. Clin Orthop, (355) Oct. 1998 pp. 200–11.Google Scholar
3. Araujo, C. G., Gonzalez, J. F., Tonino, A., RHEUMATOID ARTHRITIS AND HYDROXYAPATITE-COATED HIP PROSTHESES - FIVE YEAR RESULTS, J. Arthroplasty, 13 (6) 1998.Google Scholar
4. Barrere, F., Layrolle, P., Blitterswijk, C.A, Groot, K. de, BIOMIMETIC CALCIUM PHOSPHATE COATING ON TI6AL4V: A CRYSTAL GROWTH STUDY OF OCTACALCIUM PHOSPHATE AND INHIBITION BY MG2+ AND HCO3-. Bone 25 (2 Suppl) Aug. 1999,107S–111S.Google Scholar
5. Campbell, A. A., Fryxell, G. E., Linehan, J. C., Graff, G. L., SURFACE –INDUCED MINERALIZATION: A NEW METHOD FOR PRODUCING CALCIUM PHOSPHATE COATINGS J Biomed Mater Res 32 (1) Sept 1996, pp 111–8.Google Scholar
6. Unuma, H., Ito, K., Ota, T., Takahashi, M., PREPARATION OF HYDROXYAPATITE UNDER STERIC ACID MONOLAYERS J Am Ceram Soc 79 [9] 1996 pp. 2474–76.Google Scholar
7. Li, P., Ohtsuki, C., Kokubo, T., Nakanishi, K., Soga, N., Nakamura, T., and Yamamuro, T., EFFECTS OF IONS IN AQUEOUS MEDIA ON HYDROXYAPATITE INDUCTION BY SILICS GEL AND ITS RELEVANCE TO BIOACTIVITY OF BIOACTIVE GLASSES AND GLASS-CERAMICS J AppI Biomater 4(3) Fall 1993 pp. 221–9.Google Scholar
8. Brent Constantz, R. and Gary Osaka, C., U.S. Patent No. 5 164 187 (17 November 1992)Google Scholar
9. Brent Constantz, R., Patent, U.S. No. 5 188 670 (23 February 1993)Google Scholar
10. Hom, T., Babot, J., Delaney, D., Constantz, B. R., Ison, I. C., Quiaoit, A., A BIOMINERAL COATING BY LOW TEMPERATURE PRECIPITATION (Mater. Res. Soc. April, 1993) pp. 423.Google Scholar
11. Aberman, H. M, Jones, L. C., Baines, D. P., Villanueva, A. R., Constantz, B. R., Hungerford, D. S., Dumbleton, J. H., GAP HEALING IN A NON-WEIGHT BEARING DOG MODEL: EFFECTIVINESS OF A SOLUTION PRECIPITATED APATITE COATING (39th Annual Meeting, Orthopaedic Research Society, February 1993) p 466.Google Scholar
12. Fagan, M., Aberman, H. M., DeYoung, D. J., EFFECT OF PRECIPITATED CALCIUM PHOSPHATE COATING ON BONE FIXATION OF A P.C.A. CANINE HIP STEM AT EARLY TIME PERIODS, (ASME Advances in Bioengineering, BED-Vol.28, 1994) pp.439–440 Google Scholar
13. Aberman, H. M, Jones, L. C., Fagan, M., Hungerford, D. S., Dumbleton, J. H., THE EFFECTIVINESS OF PERI-APATITE COATINGS IN BRIDGING IMPLANT GAPS (42nd Annual Meeting, Orthopaedic Research Society, February 1996) p 526.Google Scholar
14. H. M Aberman, Goodman, S. B., Lalor, P. A., Fagan, M., Dumbleton, J. H., IN VIVO BIOSTABILITY OF A SOLUTION PRECIPITATED APATITE COATING (5TH World Biomaterials Congress, May 29 - June 2 1996) p 662.Google Scholar
15. Anderson, D. E., G. St-Jean, Richardson, D. C., Debowes, R. M., Roush, J. K., Lowry, S.R., Toll, P. W., Aberman, H. A., Sickle, D. C. Van, Hoskinson, J. J., IMPROVED OSSEOINTERACTION OF CALCIUM PHOSPHATE-COATED EXTERNAL FIXATION PINS, Acta Orthop Scand, 68, (6) 571–576 (1997).Google Scholar
16. Turner, A. S., Eckhoff, D. G., Dewell, R. D., Villanueva, A. R., Aberman, H. M, PERIAPATITE-COATED IMPLANTS IMPROVE FIXATION IN OSTEOPENIC BONE (44th Annual Meeting, Orthopaedic Research Society, March 1996) p 4–1.Google Scholar