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Nanophase Alumina/Poly(L-Lactic Acid) Composite Scaffolds for Biomedical Applications

Published online by Cambridge University Press:  11 February 2011

Aaron J. Dulgar Tulloch ,
Rena Bizios  and
Richard W. Siegel
Aaron J. Dulgar Tulloch
Affiliation:
Department of Materials Science and Engineering, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA Rensselaer Nanotechnology Center, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA
Rena Bizios
Affiliation:
Department of Biomedical Engineering, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA Rensselaer Nanotechnology Center, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA
Richard W. Siegel
Affiliation:
Department of Materials Science and Engineering, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA Rensselaer Nanotechnology Center, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA
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Abstract

Three-dimensional composites of nanophase alumina and poly(L-lactic acid) with an interconnected porous network and an overall porosity in excess of 90% are cytocompatible. Osteoblast proliferation on the nanophase ceramic/polymer composites is a function of time of cell culture and of nanoceramic loading in the biomaterial substrates.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 740: Symposium I – Nanomaterials for Structural Applications , 2002 , I6.3
Copyright
Copyright © Materials Research Society 2003

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References

REFERENCES

1. Webster, T.J., Siegel, R.W., Bizios, R., Nanostruct. Mater. 12:983 1999 Google Scholar
2. McManus, A.J., Master's Thesis, Rensselaer Poytechnic Institute, Troy, NY 2001 Google Scholar
3. Webster, T.J., Siegel, R.W., Bizios, R., Biomaterials 20:1222 1999 Google Scholar
4. Webster, T.J., Siegel, R.W., Bizios, R., Biomaterials 21:1803 2000 Google Scholar
5. Webster, T.J., Ergun, C., Doremus, R.H., Siegel, R.W., Bizios, R., Biomed, J.. Mater. Res. 51:475 2000 Google Scholar
6. Webster, T.J., Schadler, L.S., Siegel, R.W., Bizios, R., Tissue Eng. 7:291 2001 Google Scholar
7. Zhang, R., Ma, P.X., Biomed, J.. Mater. Res. 44:446 1999 Google Scholar
8. ASTM D 1621–00Google Scholar
9. Puleo, D.A., Holleran, L.H., Doremus, R.H., Bizios, R., J. Biomed. Mat. Res. 25:711 1991 Google Scholar
10. Lam, K.H., Nieuwenhuis, P., Molenaar, I., Esselbrugge, H., Feijen, J., Dijkstra, P.J., Schakenraad, J.M., J. Mater. Sci.: Matls. in Med. 5:181 1994 Google Scholar
11. Ishaug, S.L., Crane, G.M., Miller, M.J., Yasko, A.W., Yazemski, M.J., Mikos, A.G., J Biomed. Mater. Res. 36:17 1997 Google Scholar
12. Ma, P.X., Zhang, R., Xiao, G., Franceschi, R., J. Biomed. Mater. Res. 54:284 2001 Google Scholar
13. Sikavitsas, V.I., Bancroft, G.N., Mikos, A.G., J. Biomed. Mater. Res. 62:136 2002 Google Scholar