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Low-temperature Plasma Processing of Micro- and Nanostructured Materials for Biomedical Applications

Published online by Cambridge University Press:  16 May 2012

Masaaki Nagatsu
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Roman V. Bekarevich
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Alexei Balmakov
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Iuliana Motrescu
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Akihisa Ogino
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Akiko Murakawa
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Enoch Y. Park
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
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Abstract

We develop a plasma processing technique for modifying the surface properties of micro- and nanostructured materials for biomedical applications. We also investigate the physical and chemical roles of the plasma in modifying the surfaces of micro- and nanostructured materials such as magnetic nanoparticles (MNPs), carbon nanotubes (CNTs), nanophosphors, and biomolecules for various biomedical applications. We introduced amino groups onto the surfaces of graphite-encapsulated iron compound nanoparticles using a low-pressure Ar plasma pre-treatment and ammonia plasma post-treatment followed by immobilization of biomolecules, such as dextran and N-acetyllactosamine (LacNAc). The present technique was also used to introduce amino groups onto CNT dot arrays grown on Si substrates for use in biochip sensors.

Type
Research Article
Copyright
Copyright © Materials Research Society 2012

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References

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