Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-07T21:07:51.605Z Has data issue: false hasContentIssue false
  • English
  • Français

Integrating Carbon Nanotubes into Microfluidic Chips for Separating Biochemical Compounds

Published online by Cambridge University Press:  31 January 2012

Miaoxiang Chen ,
Klaus B. Mogensen ,
Peter Boggild  and
Jörg P. Kutter
Miaoxiang Chen
Affiliation:
Department of Micro and Nanotechnology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark. International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-310 Braga, Portugal. E-mail: [email protected]
Klaus B. Mogensen
Affiliation:
Department of Micro and Nanotechnology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Peter Boggild
Affiliation:
Department of Micro and Nanotechnology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Jörg P. Kutter
Affiliation:
Department of Micro and Nanotechnology, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Get access

Abstract

We present a new type of device to separate biochemical compounds wherein carbon nanotubes (CNTs) are integrated as chromatographic stationary phase. The CNTs were directly grown on the bottom of microfluidic channels on Si/SiO2 substrate by chemical vapor deposition (CVD). Acetylene was used as carbon source and Ni was employed as catalyst. For electrokinetic separations, higher electrical field strength is usually required; therefore, the CNTs were constructed in pillar-array-form by patterning Ni catalyst layer. Electrical field strength of 2.0 kV/cm has been realized, which is more than one order of magnitude higher than the one reported so far. The microfluidic chips integrated with CNTs were successfully used to separate a compound containing two Coumarin dyes, 240 mM C460 and 270 mM C480.

Keywords

Carbon NanotubesStationary PhaseMicrofluidics
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1371: Symposium S1 – Nanostructured Materials and Nanotechnology , 2012 , imrc11-1371-s1-45
Copyright
Copyright © Materials Research Society 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Arora, A., Simone, G., Salieb-Beugelaar, G. B., Kim, J. T., and Manz, A., Anal. Chem. 82, 4830 (2010).Google Scholar
2. Faure, K., Electrophoresis 31, 2499 (2010).Google Scholar
3. Nilsson, C., Birnbaum, S., Nilsson, S., J. Chromatogr. A 1168, 212 (2007).Google Scholar
4. Li, Y., Chen, Y., Xiang, R., Ciuparu, D., Pfefferle, L. D., Horvath, C., Wilkins, J. A., Anal.Chem. 77, 1398 (2005).Google Scholar
5. Weng, X., Bi, H., Liu, B., Kong, J., Electrophoresis 27, 3129 (2006).Google Scholar
6. Menna, E., Negra, F. D., Prato, M., Tagmatarchis, N., Ciogli, A., Gasparrini, F., Misiti, D., Villani, C., Carbon 44, 1609 (2006).Google Scholar
7. Goswami, S., Chromatographia 69, 473 (2009).Google Scholar
8. Mogensen, K. B., Gangloff, L., Boggild, P., Teo, K. B. K., Milne, W. I. and Kutter, J. P., Nanotechnology 20, 095503 (2009).Google Scholar
9. Mogensen, K. B., Chen, M. X., Molhave, K., Boggild, P. and Kutter, J. P., Lab Chip, 11, 2116 (2011).Google Scholar