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Flow Structure in Continuous Flow Electrophoresis Chambers

Published online by Cambridge University Press:  15 February 2011

J. A. DEIBER  and
D. A. Saville
J. A. DEIBER
Affiliation:
Department of Chemical Engineering, Princeton University, Princeton, NJ 08544
D. A. Saville
Affiliation:
Department of Chemical Engineering, Princeton University, Princeton, NJ 08544
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Abstract

There are at least two ways that hydrodynamic processes can limit continuous flow electrophoresis. One arises from the sensitivity of the flow to small temperature gradients, especially at low flow rates and power levels. This sensitivity can be suppressed, at least in principle, by providing a carefully tailored, stabilizing temperature gradient in the cooling system that surrounds the flow channel. At higher power levels another limitation arises due to a restructuring of the main flow. This restructuring is caused by buoyancy, which is in turn affected by the electro-osmotic crossflow. Approximate solutions to appropriate partial differential equations have been computed by finite difference methods. One set of results is described here to illustrate the strong coupling between the structure of the main (axial) flow and the electro-osmotic flow.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 9 , 1981 , 217
Copyright
Copyright © Materials Research Society 1982

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Footnotes

*

Present address: Instituto de Desarrollo Tecnológico, Sante Fe, Argentina

References

REFERENCES

1.Saville, D. A., Fluid Mechanics and Electrophoresis, in Physicochemical Hydrodynamics, Levich Festschrift, V. G., Spalding, D. B., ed. (Advance Publications Ltd., Guernsey, U.K. 1978) vol. II, pp. 893–912.Google Scholar
2.Saville, D. A., Fluid Mechanics of Continuous Flow Electrophoresis, in (COSPAR) SPACE RESEARCH, Rycroft, M. J., ed. (Pergamon Press, Oxford and New York 1979) vol. XIX, pp. 583–597.Google Scholar
3.Saville, D. A., Physicochemical Hydrodynamics 1, 297 (1980).Google Scholar
4.Levich, V. G., Physicochemical Hydrodynamics, (Prentice Hall, Englewood Cliffs, NJ 1962) p. 472 ff.Google Scholar