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Elastic and Viscoelastic Characterization of Polydimethylsiloxane (PDMS) for Cell-Mechanics Applications

Published online by Cambridge University Press:  01 February 2011

I-Kuan Lin
Affiliation:
[email protected], Boston University, Manufacturing Engineering, 15 Saint Marys St., Brookline, MA, 02446, United States, 6173656745
Yen-Ming Liao
Affiliation:
[email protected], National Cheng Kung University, Mechanical Engineering, No.1, Ta-Hsueh Road, Tainan, 701, Taiwan
Yan Liu
Affiliation:
[email protected], Boston University, Manufacturing Engineering, 15 Saint Marys St., Brookline, MA, 02446, United States
Kuo-Shen Chen
Affiliation:
[email protected], National Cheng Kung University, Mechanical Engineering, No.1, Ta-Hsueh Road, Tainan, 701, Taiwan
Xin Zhang
Affiliation:
[email protected], Boston University, Manufacturing Engineering, 15 Saint Marys St., Brookline, MA, 02446, United States
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Abstract

The mechanical properties of polydimethylsiloxane (PDMS) were characterized by using uniaxial compression, dynamic mechanical analysis (DMA), and nanoindentation tests as well as finite element simulation methods. A five-parameter linear solid model was used to emulate the behavior of PDMS. The study results indicated that the effect of viscoelasticity affected the PDMS pillar arrays significantly. The traditional approach for calculating the cell force basing on the linear elastic mechanics could result in considerable errors.

Type
Research Article
Copyright
Copyright © Materials Research Society 2008

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References

[1] Tan, J.L., Tien, J., Pirone, D.M. et al. , Proc. Natl. Acad. Sci., 100(2003) pp. 14841489.Google Scholar
[2] Zhao, Y. and Zhang, X., Applied Physics Letters, 87(2005), pp. 144101.Google Scholar
[3] Menard, K. P., Dynamic Mechanical Analysis, (CRC press LLC, 1999) pp. 162171.Google Scholar
[4] Riande, E., Polymer Viscoelasticity: Stress and Strain in Practice, (CRC press LLC, 1999), pp. 394 Google Scholar