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Direct-Write Construction of Tissue-Engineered Scaffolds

Published online by Cambridge University Press:  17 March 2011

Anatoly M. Kachurin
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
Robert L. Stewart
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
Kenneth H. Church
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
William L. Warren
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
John P. Fisher
Affiliation:
Department of Bioengineering, Rice University, Houston, TX 77251, U.S.A.
Antonios G. Mikos
Affiliation:
Department of Bioengineering, Rice University, Houston, TX 77251, U.S.A.
Stine-Katherine Kraeft
Affiliation:
Dana–Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, U.S.A.
Lan Bo Chen
Affiliation:
Dana–Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, U.S.A.
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Abstract

A computer-controlled xyz dispensing system called the Biological Architecture Tool (BAT) has been extensively tested in the creation of multilayered and three-dimensional biological objects: tissue scaffolds and plain and patterned cellular-array slides. The BAT dispensing system has proven its versatility and reliability in tissue engineering and biological experiments. The potential employments of modified versions of the xyz dispensers for in vivo minimally invasive surgery and other in vitro aspects of biological and medical research are discussed.

Type
Research Article
Copyright
Copyright © Materials Research Society 2002

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References

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