Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-25T15:20:56.082Z Has data issue: false hasContentIssue false
  • English
  • Français

Computational Fluid Dynamics Models of Molecularly Imprinted Materials in Microfluidic Channels

Published online by Cambridge University Press:  01 February 2011

Cindy K. Webber  and
M. Joseph Roberts
Cindy K. Webber
Affiliation:
Polymer Science and Engineering Branch, Code 4T4220D, NAVAIR, NAWCWD, China Lake, CA 93555, USA
M. Joseph Roberts
Affiliation:
Polymer Science and Engineering Branch, Code 4T4220D, NAVAIR, NAWCWD, China Lake, CA 93555, USA
Get access

Abstract

Current research will lead to rapid-prototyping of chemical sensors that utilize microfabricated molecularly imprinted (MI) materials. CFD/CAD software may be used to model flow and chemical binding properties of MI materials in microfluidic channels. Use of this type of software expedites results when changes in properties are made. The surface concentration of bound analyte on a monolithic molecularly imprinted polymer (MIP) within microfluidic channels can be modeled using its experimental binding kinetics. The time necessary to reach a detection limit is calculated and optimized as a function of flow parameters. In this report, we discuss the unique issues associated with the modeling of chemical sensors that utilize MI materials.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 723: Symposia M/O – Molecularly Imprinted Materials – Chemical and Biological Sensors-Materials and Devices , 2002 , M5.1
Copyright
Copyright © Materials Research Society 2002

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Hart, B. R.; Shea, K. J. J. Am. Chem. Soc. 123, 2072 (2001).Google Scholar
2. Welty, J., Wicks, C., and Wilson, R., Fundamentals of Momentum, Heat, and Mass Transfer, (John Wiley & Sons, Inc., 1984).Google Scholar
3. Yan, M.; Kapua, A. “Fabrication of Molecularly Imprinted Polymer Microstructures,” Anal. Chim. Acta, 435, 163–167 (2001).Google Scholar
4. Zhang, X., Jiang, X., and Sun, C., “Micro-stereolithography for polymeric and ceramic micro parts,” Sensors and Actuators, A, 77(2), 149–156 (1999).Google Scholar