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Biomimetic Preparation of ha Precursors at 37°C in Urea- and Enzyme Urease-Containing Synthetic Body Fluids

Published online by Cambridge University Press:  10 February 2011

D Bayraktar  and
A C. Tas
D Bayraktar
Affiliation:
Dept. Metal & Mat. Eng., Middle East Technical University, Ankara 06531, Turkey
A C. Tas
Affiliation:
Pulvermetall. Lab., Max-Planck-Institute, Stuttgart D-70569, Germany
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Abstract

An important inorganic phase of synthetic bone applications, calcium hydroxyapatite (HA, Ca10(PO4)6(OH)2), was prepared as a single-phase and sub-micron bioceramic powder. Carbonated HA precursors were synthesized from calcium nitrate tetrahydrate and diammonium hydrogen phosphate salts dissolved in “synthetic body fluid” (SBF) solutions, containing urea (H2NCONH2) and enzyme urease, under the biomimetic conditions of 37°C and pH 7.4, by using a novel chemical precipitation technique.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 599: Symposium DD – Mineralization in Natural & Synthetic Biomaterials , 1999 , 159
Copyright
Copyright © Materials Research Society 2000

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