Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-06T06:19:32.155Z Has data issue: false hasContentIssue false

AlGaN/GaN-sensors for Monitoring of Enzyme Activity by pH-Measurements

Published online by Cambridge University Press:  01 February 2011

Gabriel Kittler
Affiliation:
[email protected], TU Ilmenau, Institute of Micro- and Nanotechnologies, Nanotechnology, Gustav-Kirchhoff-Str. 7, Ilmenau, 98963, Germany
Armin Spitznas
Affiliation:
[email protected], Institute of Micro- and Nanotechnologies, Technical University Ilmenau, Gustav-Kirchhoff-Str. 7, Ilmenau, 98963, Germany
Benedikt Luebbers
Affiliation:
[email protected], Institute of Micro- and Nanotechnologies, Technical University Ilmenau, Gustav-Kirchhoff-Str. 7, Ilmenau, 98963, Germany
Vadim Lebedev
Affiliation:
[email protected], Institute of Micro- and Nanotechnologies, Technical University Ilmenau, Gustav-Kirchhoff-Str. 7, Ilmenau, 98963, Germany
Dennis Wegener
Affiliation:
[email protected], Institute for Physical High Technology Jena, P.O. Box 100239, Jena, 07702, Germany
Michael Gebinoga
Affiliation:
[email protected], Center for Innovation Competence MacroNano®, Microfluidics and Biosensors, Gustav-Kirchhoff-Str. 7, Ilmenau, 98693, Germany
Frank Weise
Affiliation:
[email protected], Center for Innovation Competence MacroNano®, Microfluidics and Biosensors, Gustav-Kirchhoff-Str. 7, Ilmenau, 98693, Germany
Andreas Schober
Affiliation:
[email protected], Center for Innovation Competence MacroNano®, Microfluidics and Biosensors, Gustav-Kirchhoff-Str. 7, Ilmenau, 98693, Germany
Oliver Ambacher
Affiliation:
[email protected], Institute of Micro- and Nanotechnologies, Technical University Ilmenau, Gustav-Kirchhoff-Str. 7, Ilmenau, 98963, Germany
Get access

Abstract

GaN based pH-sensors were used to measure the reaction and the kinetics of a lipase assay producing caprylic acid. Sensor structures consist of an AlGaN/GaN-heterostructure grown by plasma-induced molecular beam epitaxy with a thin GaN cap layer. The carrier concentration of the two-dimensional electron gas is manipulated by changing the surface potential due to changes in pH value.

Type
Research Article
Copyright
Copyright © Materials Research Society 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Ambacher, O., J. Phys. D: Appl. Phys. 31, 2653 (1998).Google Scholar
2. Bergveld, P., IEEE Trans. Biomed. Eng. 17, 70 (1970).Google Scholar
3. Steinhoff, G., Hermann, M., Schaff, W. J., Eastman, L. F., Stutzmann, M., and M. Eickhoff, Appl. Phys. Lett. 83, 177 (2003).Google Scholar
4. Bayer, M., Uhl, C., and Vogl, P., J. Appl. Phys. 97, 033703 (2005).Google Scholar
5. Bergveld, P., Sibbald, A., Compr. Analyt. Chem. Vol.23, Elsevier (1988).Google Scholar
6. Steinhoff, G. et al., Appl. Phys. Lett. 86, 033901 (2005).Google Scholar
7. Kang, B. S. et al., Appl. Phys. Lett. 87, 023508 (2005).Google Scholar
8. Jaeger, K. E., Eggert, T., Curr. Opin. Biotechnol. 13, 390, (2002).Google Scholar