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Theranostic applications of organic nanoparticles for cancer treatment

Published online by Cambridge University Press:  13 March 2014

Ji Young Yhee ,
Sohee Son ,
Namho Kim ,
Kuiwon Choi  and
Ick Chan Kwon
Ji Young Yhee
Affiliation:
Korea Institute of Science and Technology; [email protected]
Sohee Son
Affiliation:
Korea Institute of Science and Technology; [email protected]
Namho Kim
Affiliation:
Korea Institute of Science and Technology; [email protected]
Kuiwon Choi
Affiliation:
Korea Institute of Science and Technology; [email protected]
Ick Chan Kwon
Affiliation:
Korea Institute of Science and Technology; [email protected]
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Abstract

Research in nanotechnology-based molecular imaging and targeted drug delivery has resulted in a noticeable progress in cancer theranosis, the simultaneous application of cancer therapy and diagnosis. Theranostic nanoparticles (NPs) have been developed using diverse base materials, and organic materials are of major interest in the synthesis and preparation of these NPs. A variety of organic NPs have their own advantages, depending on the physiochemical and biological properties of the base materials. This article reviews recent developments in organic NPs, which are grouped into four major kinds of base materials: lipids, polysaccharides, peptides/proteins, and synthetic polymers. The advantageous properties of frequently used base materials and practical performance of the various organic NPs in vivo are discussed. These theranostic NPs offer new opportunities for effective cancer treatment.

Keywords

Biomaterialbiomedicalorganicpolymernanostructure
Type
Research Article
Information
MRS Bulletin , Volume 39 , Issue 3: Organic Nanoparticles for Drug Delivery and Imaging , March 2014 , pp. 239 - 249
Copyright
Copyright © Materials Research Society 2014 

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