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Bioactive glass-ceramic scaffolds: Processing and properties

Published online by Cambridge University Press:  06 March 2017

Elena Boccardi
Affiliation:
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; [email protected]
Francesca E. Ciraldo
Affiliation:
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; [email protected]
Aldo R. Boccaccini
Affiliation:
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; [email protected]
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Abstract

Bioactive glasses and related bioactive glass-ceramics have been used for over three decades in biomedical applications such as bulk, particulate, or coatings materials. More recently, highly porous bioactive glass-ceramic scaffolds for bone-tissue engineering have also been developed from selected compositions of bioactive glasses. Current bioactive glass-ceramic scaffolds are characterized by an open porous network, high bioactivity, and mechanical properties similar to those of trabecular bone. This article reviews the latest achievements in the development of porous bioactive glass-ceramics intended for bone-tissue engineering applications, highlighting the fabrication technologies and scaffold properties. Improvements in the mechanical properties of bioactive glass-ceramic scaffolds exhibiting high bioactivity have been achieved by different approaches in the last 10 years. Relevant long-term in vivo studies are required to confirm the suitability of such bioactive glass-ceramic scaffolds in clinical applications.

Type
Research Article
Copyright
Copyright © Materials Research Society 2017 

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