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The Materials Science of Bone: Lessons from Nature for Biomimetic Materials Synthesis

Published online by Cambridge University Press:  31 January 2011

Michelle L. Oyen
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Abstract

There has been considerable recent interest in natural bone as a material, due in part to its interesting combination of mechanical properties: bone is stiff and tough but lightweight. This unusual combination of properties results from a nanocomposite structure of approximately equal volumes of mineral and hydrated organic matter. Much recent effort has been focused on the structure, properties, and performance at different length scales relative to the hierarchical organization of bone. Historically, such bone research has emphasized clinical and medical aspects, including engineering materials for bone augmentation or replacement, bone–biomaterial interactions and interfaces, and more recently, scaffolds for bone tissue engineering. However, within the fast-growing biomimetics field, the bone extracellular matrix is taken as a model for materials development. Efforts have been made both to mimic the bony material itself as well as to mimic the process by which bone forms.

Type
Research Article
Information
MRS Bulletin , Volume 33 , Issue 1: Advancing Materials and Technologies for Water Purification , January 2008 , pp. 49 - 55
Copyright
Copyright © Materials Research Society 2008

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References

1.Mayer, G., Science 310, 1144 (2005).CrossRefGoogle Scholar
2.Tang, Z., Kotov, N.A., Magonov, S., Ozturk, B., Nat. Mater. 2, 413 (2003).CrossRefGoogle Scholar
3.Vincent, J.F.V., Wegst, U.G.K., Arthropod Struct. Dev. 33, 187 (2004).CrossRefGoogle Scholar
4.Green, D., Walsh, D., Mann, S., Oreffo, R.O.C., Bone 30, 810 (2002).CrossRefGoogle ScholarPubMed
5.Vincent, J.F., Bogatyreva, O.A., Bogatyrev, N.R., Bowyer, A., Pahl, A.K., J. R. Soc. Interface 3, 471 (2006).CrossRefGoogle Scholar
6.Sanford, K., Kumar, M., Curr. Opin. Biotechnol. 16, 416 (2005).CrossRefGoogle Scholar
7.Lagziel-Simis, S., Cohen-Hadar, N., Moscovich-Dagan, H., Wine, Y., Freeman, A., Curr. Opin. Biotechnol. 17, 569 (2006).CrossRefGoogle Scholar
8.Mann, S., Weiner, S., J. Struct. Biol. 126, 179 (1999).CrossRefGoogle Scholar
9.Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J.D., Molecular Biology of the Cell (Garland Publishing, New York, ed. 3, 1994).Google Scholar
10.Leventouri, T., Biomaterials 27, 3339 (2006).CrossRefGoogle Scholar
11.Deer, W.A., Howie, R.A., Zussman, J., An Introduction to the Rock-Forming Minerals (Longman, London, 1966).Google Scholar
12.Bonucci, E., Mechanical Testing of Bone and the Bone–Implant Interface, An, Y.H., Draughn, R.A., Eds. (CRC Press, Boca Raton, 2000) p. 3.Google Scholar
13.Currey, J.D., Bones: Structure and Mechanics (Princeton University Press, Princeton, NJ, 2002).CrossRefGoogle Scholar
14.Kaplan, F.S., Hayes, W.C., Keaveny, T.M., Boskey, A., Einhorn, T.A., Iannotti, J.P., Orthopaedic Basic Science, Simon, S.R., Ed. (American Academy of Orthopaedic Surgeons, Rosemont, IL, 1994) p. 127.Google Scholar
15.Huiskes, R., van Rietbergen, B., Basic Orthopaedic Biomechanics and Mechanobiology, Mow, V.C., Huiskes, R., Eds. (Lippincott, Williams, and Wilkins, Philadelphia, ed. 3, 2005) p. 123.Google Scholar
16.Vater, C.A., Harris, E.D., Siegel, R.C., Biochem. J. 181, 639 (1979).CrossRefGoogle Scholar
17.Salgado, A.J., Coutinho, O.P., Reis, R.L., Macromol. Biosci. 4, 743 (2004).CrossRefGoogle Scholar
18.Weiner, S., Wagner, H.D., Ann. Rev. Mater. Sci. 28, 271 (1998).CrossRefGoogle Scholar
19.Lakes, R.S., Nature 361, 511 (1993).CrossRefGoogle Scholar
20.Currey, J.D., Science 309, 253 (2005).CrossRefGoogle ScholarPubMed
21.Gibson, L.J., Ashby, M.F., Cellular Solids: Structure and Properties (Cambridge University Press, Cambridge, UK, ed. 2, 1997).CrossRefGoogle Scholar
22.Boskey, A.L., Calcif. Tissue Int. 63, 179 (1998).CrossRefGoogle Scholar
23.Boskey, A.L., Connect. Tissue Res. 44 (1), 5 (2003).CrossRefGoogle Scholar
24.Boskey, A.L., J. Cell. Biochem. (Suppl). 30–31, 83 (1998).3.0.CO;2-F>CrossRefGoogle Scholar
25.Skinner, H.C.W., Jahren, A.H., Biogeochemistry, Vol. 8 of Treatise on Geochemistry, Holland, F., Turekian, K.K., Eds. (Elsevier, New York. 2003) p. 117.Google Scholar
26.Jaeger, C., Groom, S.N., Bowe, E.A., Horner, A., Davies, M.E., Murray, R.C., Duer, M.J., Chem. Mater. 17, 3059 (2005).CrossRefGoogle Scholar
27.Cowin, S.C., Ed., Bone Mechanics Handbook (CRC Press, Boca Raton, FL, ed. 2, 2001).CrossRefGoogle Scholar
28.An, Y.H., Draughn, R.A., Eds., Mechanical Testing of Bone and the Bone–Implant Interface (CRC Press, Boca Raton, FL, 2000).Google Scholar
29.Balooch, G., Balooch, M., Nalla, R.K., Schilling, S., Filvaroff, E.H., Marshall, G.W., Marshall, S.J., Ritchie, R.O., Derynck, R., Alliston, T., Proc. Natl. Acad. Sci. U.S.A. 102, 18813 (2005).CrossRefGoogle Scholar
30.Ebenstein, D., Pruitt, L., Nano Today 1, 26 (2006).CrossRefGoogle Scholar
31.Donnelly, E., Williams, R.M., Downs, S.A., Dickinson, M.E., Baker, S.P., van der Meulen, M.C.H., J. Mater. Res. 21, 2106 (2006).CrossRefGoogle Scholar
32.Buehler, M.J., Nanotechnology 18, 295102 (2007).CrossRefGoogle Scholar
33.Hoffler, C.E., Moore, K.E., Kozloff, K., Zysset, P.K., Brown, M.B., Goldstein, S.A., Bone 26, 603 (2000).CrossRefGoogle ScholarPubMed
34.Rho, J.Y., Zioupos, P., Currey, J.D., Pharr, G.M., Bone 25, 295 (1999).CrossRefGoogle Scholar
35.Turner, C.H., Rho, J.-Y., Takano, Y., Tsui, T.Y., Pharr, G.M., J. Biomech. 32, 437 (1999).CrossRefGoogle Scholar
36.Currey, J.D., J. Biomech. 36, 1487 (2003).CrossRefGoogle Scholar
37.Katz, J.L., J. Biomech. 4, 455 (1971).CrossRefGoogle Scholar
38.Jager, I., Fratzl, P., Biophys. J. 79, 1737 (2000).CrossRefGoogle Scholar
39.Kotha, S.P., Guzelsu, N., J. Theor. Biol. 219, 269 (2002).CrossRefGoogle Scholar
40.Hellmich, C., Ulm, F.-J., J. Biomech. 35, 1199 (2002).CrossRefGoogle Scholar
41.Hellmich, C., Ulm, F.-J., Dormieux, L., Biomech. Model. Mechanobiol. 2, 219 (2004).CrossRefGoogle Scholar
42.Ji, B., Gao, H., J. Mech. Phys. Solids 52, 1963 (2004).CrossRefGoogle Scholar
43.Puxkandl, R., Zizak, I., Paris, O., Keckes, J., Tesch, W., Bernstorff, S., Purslow, P., Fratzl, P., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 357, 191 (2002).CrossRefGoogle Scholar
44.An, K.N., Sun, Y.L., Luo, Z.P., Biorheology 41, 239 (2004).Google Scholar
45.Freeman, J.W., Silver, F.H., J. Theor. Biol. 229, 371 (2004).CrossRefGoogle Scholar
46.Vincent, J., Structural Biomaterials, Rev. Ed. (Princeton University Press, Princeton, NJ, 1990).Google Scholar
47.Clarke, D.R., J. Am. Ceram. Soc. 75, 739 (1992).CrossRefGoogle Scholar
48.Sasaki, N., Enyo, A., J. Biomech. 28, 809 (1995).CrossRefGoogle Scholar
49.Cowin, S.C., J. Biomech. 32, 217 (1999).CrossRefGoogle Scholar
50.Yamashita, J., Furman, B.R., Rawls, H.R., Wang, X., Agrawal, C.M., J. Biomed. Mater. Res. 58, 47 (2001).3.0.CO;2-U>CrossRefGoogle Scholar
51.Bembey, A.K., Bushby, A.J., Boyde, A., Ferguson, V.L., Oyen, M.L., J. Mater. Res. 21, 1962 (2006).CrossRefGoogle Scholar
52.Ager, J.W., Balooch, G., Ritchie, R.O., J. Mater. Res. 21, 1878 (2006).CrossRefGoogle Scholar
53.Taylor, D., Hazenberg, J.G., Lee, T.C., Nat. Mater. 6, 263 (2007).CrossRefGoogle Scholar
54.Oyen, M.L., Ko, C.-C., J. Mater. Sci. Mater. Med. 18, 623 (2007).CrossRefGoogle Scholar
55.Tai, K., Dao, M., Suresh, S., Palazoglu, A., Ortiz, C., Nat. Mater. 6, 454 (2007).CrossRefGoogle Scholar
56.Jaasma, M.J., Bayraktar, H.H., Niebur, G.L., Keaveny, T.M., J. Biomech. 35, 237 (2002).CrossRefGoogle Scholar
57.Becker, R.O., Marino, A.A., Electromagnetism and Life (State University of New York Press, Albany, 1982).Google Scholar
58.Noris-Suarez, K., Lira-Olivares, J., Ferreira, A.M., Feijoo, J.L., Suarez, N., Hernandez, M.C., Barrios, E., Biomacromolecules 8, 941 (2007).CrossRefGoogle Scholar
59.Wegst, U.G.K., Ashby, M.F., Philos. Mag. 84, 2167 (2004).CrossRefGoogle Scholar
60.Hollister, S.J., Nat. Mater. 4, 518 (2005).CrossRefGoogle Scholar
61.Karp, J.M., Dalton, P.D., Shoichet, M.S., MRS Bull. 28 (4), 301 (2003).CrossRefGoogle Scholar
62.Orban, J.M., Marra, K.G., Hollinger, J.O., Tissue Eng. 8, 529 (2002).CrossRefGoogle Scholar
63.Meyer, U., Joos, U., Wiesmann, H.P., Int. J. Oral Maxillofac. Surg. 33, 325 (2004).CrossRefGoogle Scholar
64.Wiesmann, H.P., Joos, U., Meyer, U., Int. J. Oral Maxillofac. Surg. 33, 523 (2004).CrossRefGoogle Scholar
65.Meyer, U., Joos, U., Wiesmann, H.P., Int. J. Oral Maxillofac. Surg. 33, 635 (2004).CrossRefGoogle Scholar
66.Sharma, B., Elisseeff, J.H., Ann. Biomed. Eng. 32, 148 (2004).CrossRefGoogle Scholar
67.Liu, X., Ma, P.X., Ann. Biomed. Eng. 32, 477 (2004).CrossRefGoogle Scholar
68.Anseth, K.S., Burdick, J.A., MRS Bull. 27 (2), 130 (2002).CrossRefGoogle Scholar
69.Harley, B.A., Leung, J.H., Silva, E.C., Gibson, L.J., Acta Biomater. 3, 463 (2007).CrossRefGoogle Scholar
70.Landi, E., Tampieri, A., Celotti, G., Langenati, R., Sandri, M., Sprio, S., Biomaterials 26, 2835 (2005).CrossRefGoogle Scholar
71.Zhang, S., Nat. Biotechnol. 21, 1171 (2003).CrossRefGoogle Scholar
72.Tampieri, A., Celotti, G., Landi, E., Anal. Bioanal. Chem. 381, 568 (2005).CrossRefGoogle Scholar
73.Tampieri, A., Sandri, M., Landi, E., Celotti, G., Roveri, N., Mattioli-Belmonte, M., Virgili, L., Gabbanelli, F., Biagini, G., Acta Biomater. 1, 343 (2005).CrossRefGoogle Scholar
74.Roach, P., Eglin, D., Rohde, K., Perry, C.C., J. Mater. Sci. Mater. Med. 18, 1263 (2007).CrossRefGoogle Scholar
75.Shin, H., Jo, S., Mikos, A.G., Biomaterials 24, 4353 (2003).CrossRefGoogle Scholar
76.Song, J., Malathong, V., Bertozzi, C.R., J. Am. Chem. Soc. 127, 3366 (2005).CrossRefGoogle Scholar
77.Hartgerink, J.D., Beniash, E., Stupp, S.I., Science 294, 1684 (2001).CrossRefGoogle Scholar
78.Chang, M.C., Ko, C.C., Douglas, W.H., Biomaterials 24, 2853 (2003).CrossRefGoogle Scholar
79.Bernhardt, A., Lode, A., Boxberger, S., Pompe, W., Gelinsky, M., J. Mater. Sci. Mater. Med. (June 28, 2007).Google Scholar
80.Manjubala, I., Scheler, S., Bossert, J., Jandt, K.D., Acta Biomater. 2, 75 (2006).CrossRefGoogle Scholar
81.Li, C., Vepari, C., Jin, H.J., Kim, H.J., Kaplan, D.L., Biomaterials 27 (16), 3115 (2006).CrossRefGoogle Scholar
82.Subburaman, K., Pernodet, N., Kwak, S.Y., DiMasi, E., Ge, S., Zaitsev, V., Ba, X., Yang, N.L., Rafailovich, M.. Proc. Natl. Acad. Sci. U.S.A. 103, 14672 (2006).CrossRefGoogle Scholar
83.Ko, C.C., Oyen, M.L., Fallgatter, A.M., Kim, J.-H., Douglas, W.H., Fricton, J., Hu, W.-S., J. Mater. Res. 21, 3090 (2006).CrossRefGoogle Scholar
84.Toohey, K.S., Sottos, N.R., Lewis, J.A., Moore, J.S., White, S.R.. Nat. Mater. 6, 581 (2007).CrossRefGoogle Scholar
85.Fratzl, P., J. R. Soc. Interface. 4, 637 (2007).CrossRefGoogle Scholar