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The Application of Computational Modeling to Pharmaceutical Materials Science

Published online by Cambridge University Press:  31 January 2011

Carl Wassgren  and
Jennifer Sinclair Curtis
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Abstract

Computational modeling is a ubiquitous technique in materials science, but until recently this approach has not been widely applied to the drug development process. The formation of particles, their kinematics, and their response to processing stresses are increasingly being studied using computational techniques (computational fluid dynamics and discrete element analysis). These computational techniques can be predictive tools to guide scientists who are designing pharmaceutical dosage forms with specific macroscopic properties. This article gives an overview of the types of computational methods that are used in pharmaceutical materials science and provides examples of their application to some problems from the literature and the authors' own work.

Keywords

biomedicalparticlepowdersimulation
Type
Research Article
Information
MRS Bulletin , Volume 31 , Issue 11: Pharmaceutical Materials Science , November 2006 , pp. 900 - 904
Copyright
Copyright © Materials Research Society 2006

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