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Surface-Functionalizing Metal, Metal Oxide and Semiconductor Nanocrystals with a Multi-coordinating Polymer Platform

Published online by Cambridge University Press:  20 May 2016

Wentao Wang ,
Xin Ji ,
Anshika Kapur  and
Hedi Mattoussi
Wentao Wang
Affiliation:
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306
Xin Ji
Affiliation:
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306
Anshika Kapur
Affiliation:
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306
Hedi Mattoussi*
Affiliation:
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306
*
*(Email: [email protected])
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Abstract

We introduce a new set of multifunctional metal-coordinating polymers as ligands for the surface functionalization of three different inorganic nanocrystals: luminescent quantum dots (QDs), magnetic iron oxide nanocrystals and metal gold nanoparticles. The ligand design relies on the introduction of a large but controllable number of anchoring groups, hydrophilic moieties and reactive functionalities all in the same polymer chain, via a one-step nucleophilic addition reaction. Nanocrystals capped with these polymer ligands exhibit long-term stability over a broad range of biological conditions. Furthermore, when zwitterion groups are introduced as hydrophilic blocks, this yields a compact ligand coating that allows conjugation of biomolecules to the nanocrystals via metal-histidine self-assembly. The resulting hydrophilic nanocrystals have been used to develop a few specific sensing platforms targeting soluble iron ions and cysteine.

Keywords

absorptionphotoemissionnanostructure
Type
Articles
Information
MRS Advances , Volume 1 , Issue 56: Biomaterials and Soft Materials/Engaged Learning of Materials Science and Engineering in the 21st Century , 2016 , pp. 3741 - 3747
Copyright
Copyright © Materials Research Society 2016 

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References

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