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A New Graphene Quantum Dot Sensor for Estimating an Antibiotic Concentration

Published online by Cambridge University Press:  10 January 2018

N.N.N. Ahamed ,
W. Fan ,
M. Schrlau  and
K.S.V. Santhanam
N.N.N. Ahamed
Affiliation:
School of Chemistry and Materials Science, Rochester Institute of Technology, Rochester, NY 14623
W. Fan
Affiliation:
School of Chemistry and Materials Science, Rochester Institute of Technology, Rochester, NY 14623
M. Schrlau
Affiliation:
Department of Mechanical Engineering, Rochester Institute of Technology, Rochester, NY 14623
K.S.V. Santhanam*
Affiliation:
School of Chemistry and Materials Science, Rochester Institute of Technology, Rochester, NY 14623
*
*Corresponding author:[email protected]
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Abstract

The graphene quantum dots (GQD) are unique for several different applications especially in the area of sensors as they provide a platform for large surface area on which sensing material can be attached. We wish to report here a new analytical method for sensing ciprofloxacin (CPFX) antibiotic using GQD electrode in differential pulse voltammetry (DPV) which is based on the ferric ion interaction with CPFX. Ferric ion undergoes a well defined one electron reduction at GQD electrode in DPV at Ep=0.310 V vs saturated calomel electrode (SCE) with a peak width of 0.100 V. When nanomolar to micromolar concentrations of CPFX is present in the electrolytic bath, the ferric ion reduction peak decreases with the appearance of three new peaks at EpI=0.200 V, EpII=0.050 V and EpIII= -0.085V. The three peaks are attributed to the three stages of binding of CPFX with three positive charges of ferric ion. The decrease of the ferric ion peak at 0.31 V is proportional to the concentration of CPFX. Due to large surface area of GQD, the CPFX bound ferric ion shows enhanced currents in comparison to glassy carbon electrode. The sensor is fabricated by depositing GQD containing known concentration of ferric ion. The sensor response to different concentrations of CPFX is measured for an analytical purpose.

Keywords

electronic materialsensorsurface chemistry
Type
Articles
Information
MRS Advances , Volume 3 , Issue 15-16: Nanomaterials , 2018 , pp. 825 - 830
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Copyright
Copyright © Materials Research Society 2018 

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References

REFERENCES

Gayen, P. and Chaplin, B. P., ACS Appl. Mater. Interfaces 8 (3), 1615 (2016).Google Scholar
Heidelbaugh, J.J. and Holmstrom, H., J. Family Practice 62 (4), 191 (2013).Google Scholar
Ji, H.Y., Jeong, D., Kim, Y.H., Sohn, D., and Lee, H.S., J. Pharm. Biomed. Anal. 41, 622 (2006).CrossRefGoogle Scholar
Carlucci, G., J. Chromatogr. 812, 343 (1998).Google Scholar
Pascual-Reguera, M.I., Perez Parras, G. and Molina Díaz, A., J. Pharm. Biomed. Anal. 35, 689 (2004).Google Scholar
Navalón, A., Ballesteros, O., Blanc, R., , R. and Vílchez, J.L., Talanta 52, 845 (2000).Google Scholar
Montes, R.H.O., Marra, M.C., Rodrigues, M.M., Richter, E.M., Munoz, R.A., Electroanalysis 26, 432 (2014).Google Scholar
Snitkoff, G.G., Grabe, D. W., Holt, R. and Bailie, G.R., J. Immunoassay 19, 227 (1998).Google Scholar
Sun, H., Li, L. and Chen, X., Anal. Bioanal. Chem. 384, 1314 (2006).Google Scholar
Radi, A., El Ries, M. and Kandil, S., Anal. Chim. Acta 495, 61 (2003).Google Scholar
Geim, A.K. and Novoselov, K.S., Nat. Mater. 6, 183–191 (2007).Google Scholar
Santhanam, K.S.V., Kandlikar, S., Valentina, M. and Yang, Y., Electrochemical Process for Producing Graphene, Graphene oxide, Metal Composites, and Coated Substrates. U.S. Patent 20160017502 A1, January 21, 2016. Patent No. 9840782, Issue date 12/12/17.Google Scholar
Protich, Z., Wong, P. and Santhanam, K.S.V., J. Power Sources 332, 337 (2016).CrossRefGoogle Scholar
Merlia, D., Profumo, A. and Dossib, C., J. Pharmaceutical Analysis 2 (6), 450 (2012).Google Scholar
Carabineiro, S.A.C., Thavorn-amornsri, T., Pereira, M.F.R., Serpc, P., Figueiredo, J.L., Catalysis Today 186, 29 (2012)Google Scholar
Bhongade, B., Talath, S. and Dhaneswar, S., Int. J. Spectroscopy 2014, 294612 (2014).Google Scholar
Pupkevich, V., Glibin, V. and Karamanev, D., J. Solid State Electrochemistry 11, 1429 (2007).Google Scholar
Patra, N., Esan, D.A. and Kra, P., J. Phys. Chem. C 117, 10750 (2013)Google Scholar