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Effect of some organic binders on the mechanical strength of hydroxyapatite-based biocements
Published online by Cambridge University Press: 24 October 2018
Abstract
In the present study, aiming to control the setting reaction and to increase the strength of hydroxyapatite-based biocements, gelatin, citric acid and malonic acid, and combinations of them, were used as binders. The mechanical strength of the developed biocements was evaluated after 1 to 15 days of exposure (aging) to air with 100% relative humidity at 37-40 °C. Especially for the case of gelatin, the mechanical properties of the biocements increased as a function of aging time in the humid environment. In this case, the standard compressive strength increased from ∼19 to ∼40 MPa, while the diametral compressive strength increased from ∼2 to ∼12 MPa, between day 1 and day 15 of aging. These values are similar to those reported in the past for HAp-containing biocements added with a variety of organic or inorganic binders. However, the resulting setting times were too long. Thus, it was proposed that crosslinking of gelatin by a suitable chemical agent during the application of the prepared HAp-based biocements could be a potential way to control their handling and setting characteristics, while preserving their good mechanical properties, good biocompatibility, and good solubilization characteristics in the presence of biological fluids.
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- Articles
- Information
- MRS Advances , Volume 3 , Issue 62: International Materials Research Congress XXVII , 2018 , pp. 3729 - 3734
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- Copyright © Materials Research Society 2018
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