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Effect of Experimental Conditions on the Chemical Composition of Hydroxyapatite Synthesized by Chemical Precipitation

Published online by Cambridge University Press:  28 January 2018

Jorge López-Cuevas ,
Juan C. Rendón-Angeles ,
José L. Rodríguez-Galicia  and
Carlos A. Gutiérrez-Chavarría
Jorge López-Cuevas*
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
Juan C. Rendón-Angeles
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
José L. Rodríguez-Galicia
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
Carlos A. Gutiérrez-Chavarría
Affiliation:
CINVESTAV-IPN, Unidad Saltillo, Calle Industria Metalúrgica No. 1062, Parque Industrial Saltillo - Ramos Arizpe, Ramos Arizpe, Coahuila, México, CP25900
*
*Corresponding author; Tel. +52 844 4389600; E-mail address: [email protected]
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Abstract

Hydroxyapatite [HAp, Ca5(PO4)3(OH)] was synthesized by chemical precipitation, using H3PO4 and Ca(OH)2 as chemical precursors. The precursors were slowly mixed in suitable proportions aiming to obtain Ca/P molar ratios of 1.5, 1.67 or 2.0 in the reacting suspension. This was followed by 21.5 h of aging. Both reaction and aging stages were carried out under an atmosphere of still ambient air and under continuous stirring, either at room temperature, 60 or 90 °C. The precipitates were characterized by ICP-AES and XRD. The results suggested that the most suitable Ca/P molar ratio for the production of pure phase HAp is Ca/P = 1.67, as long as the initial Ca(OH)2 particle size and/or the suspension pH are carefully controlled, especially when the synthesis is carried out above room temperature.

Keywords

biomaterialchemical synthesisbone
Type
Articles
Information
MRS Advances , Volume 2 , Issue 61: International Materials Research Congress XXV , 2017 , pp. 3851 - 3857
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Copyright
Copyright © Materials Research Society 2018 

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