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Development of a facile one-pot synthesis method for an ingestible pH sensitive actuator

Published online by Cambridge University Press:  07 October 2019

Alex Keller ,
Holly Warren  and
Marc in het Panhuis Open the ORCID record for Marc in het Panhuis [Opens in a new window]
Alex Keller
Affiliation:
School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.
Holly Warren
Affiliation:
ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, Wollongong, NSW 2522, Australia.
Marc in het Panhuis*
Affiliation:
School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia. ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, Wollongong, NSW 2522, Australia.
*
*(Email: [email protected])
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Abstract

Edible devices are an emergent technology and in this paper the simplicity and efficacy that poly(acrylic acid)/calcium hydroxide possess in creating a pH sensitive ingestible actuator which responds to acidic environments such as gastric fluid is demonstrated. It was found that poly(acrylic acid)/calcium hydroxide hydrogels exhibit reversible actuation upon submerging in 0.1 M sodium citrate for 2 hours. Our results show that these hydrogels can restore their compressive stress to 0.19 ± 0.06 MPa, swelling ratio to 26 ± 2 and volume to 56% ± 3% of its original volume. This work offers new possibilities for developments in a variety of fields such as drug delivery, 4D printed materials, soft robotics and edible devices.

Keywords

sol-gelbiomaterial
Type
Articles
Information
MRS Advances , Volume 5 , Issue 17: Soft Materials and Biomaterials , 2020 , pp. 881 - 889
Copyright
Copyright © Materials Research Society 2019

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