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Effect of carbonate incorporation on the hydroxyl content of hydroxylapatite

Published online by Cambridge University Press:  05 July 2018

J. D. Pasteris ,
C. H. Yoder ,
M. P. Sternlieb  and
S. Liu
J. D. Pasteris*
Affiliation:
Department of Earth and Planetary Sciences and Center for Materials Innovation, Washington University in St Louis, St Louis, Missouri 63130-4899, USA
C. H. Yoder
Affiliation:
Department of Chemistry, Franklin and Marshall College, Lancaster, Pennsylvania 17603, USA
M. P. Sternlieb
Affiliation:
Department of Chemistry, Franklin and Marshall College, Lancaster, Pennsylvania 17603, USA
S. Liu
Affiliation:
Department of Earth and Planetary Sciences and Center for Materials Innovation, Washington University in St Louis, St Louis, Missouri 63130-4899, USA
*
*E-mail: [email protected]
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Abstract

Mechanisms for the incorporation of carbonate into minerals of the apatite group have been explored in both the geological and medical literature. An important problem with respect to biological apatite, which requires further clarification, is the hydroxyl content of the carbonatedapatite of bone. Recent studies reveal bone apatite to contain only ∼20 mol.% of the hydroxyl content of stoichiometric hydroxylapatite, with negligible chloride or fluoride. We investigated the hypothesis that the development of vacancies in the hydroxyl channel sites is a charge-balancingmechanism for the substitution of carbonate ions into hydroxylapatite. Raman spectroscopic analyses of synthetic carbonated apatites (containing 1 to >15 wt.% carbonate) show that their hydroxyl ion concentration correlates inversely with carbonate concentration. The specific relationshipbetween carbonate and hydroxyl concentration in these samples closely follows the theoretical relationship defined by type-B substitution of carbonate for phosphate in the apatite structure. However, the 6–8 wt.% carbonate concentration in bone apatite falls far short of accounting forall of the hydroxyl depletion that occurs in bone apatite. Some of the additional hydroxyl depletion in bone apatite might result from substitution of Na+ for Ca2+, but further mechanism(s), perhaps (HPO4)2– substitution, must also play a significantrole.

Keywords

hydroxylapatitecalcium phosphatebonehydroxyl depletioncarbonated apatite
Type
Research Article
Information
Mineralogical Magazine , Volume 76 , Issue 7 , December 2012 , pp. 2741 - 2759
Copyright
Copyright © The Mineralogical Society of Great Britain and Ireland 2016

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Footnotes

†

Current address: 1 Brandenburg Building, Hershey, Pennsylvania 17033, USA

‡

Current address: 506 Via Colinas, Westlake Village, California 91362, USA

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