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Diagnostics of the AML with immunophenotypical data
Published online by Cambridge University Press: 15 May 2008
Abstract
Patients with acute myeloblastic leukemia (AML) are divided according to the French American British (FAB) classification into eight subgroups (M0 to M7) on the basis of their degree of maturation/differentiation. However, even if immunophenotypical characterization by flow cytometry is routinely used to distinguish between AML and acute lymphoblastic leukemia (ALL), it is not yet well established for the identification within the AML subgroups. Here we show that certain subgroups of AML can be identified with a good accuracy (80% of the patients we analyzed) by means of the expression of specific markers.
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- Research Article
- Information
- Mathematical Modelling of Natural Phenomena , Volume 1 , Issue 2: Hematopoiesis and blood diseases , 2006 , pp. 104 - 123
- Copyright
- © EDP Sciences, 2006
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