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Models of Self-Organizing Bacterial Communities and Comparisonswith Experimental Observations

Published online by Cambridge University Press:  03 February 2010

A. Marrocco ,
H. Henry ,
I. B. Holland ,
M. Plapp ,
S. J. Séror  and
B. Perthame
A. Marrocco
Affiliation:
INRIA Paris-Rocquencourt, BANG, BP105, F78153 LeChesnay cedex
H. Henry
Affiliation:
Physique de la Matière Condensée, École Polytechnique, CNRS, F-91128 Palaiseau
I. B. Holland
Affiliation:
Institut de Génétique et Microbiologie, CNRS UMR 8621, Univ. Paris-Sud, F-91405 Orsay
M. Plapp
Affiliation:
Physique de la Matière Condensée, École Polytechnique, CNRS, F-91128 Palaiseau
S. J. Séror
Affiliation:
Institut de Génétique et Microbiologie, CNRS UMR 8621, Univ. Paris-Sud, F-91405 Orsay
B. Perthame*
Affiliation:
INRIA Paris-Rocquencourt, BANG, BP105, F78153 LeChesnay cedex Univ. Pierre et Marie Curie, Laboratoire J.-L. Lions, CNRS UMR 7598
*
*Corresponding author. E-mail:[email protected]
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Abstract

Bacillus subtilis swarms rapidly over the surface of a synthetic mediumcreating remarkable hyperbranched dendritic communities. Models to reproduce such effectshave been proposed under the form of parabolic Partial Differential Equations representingthe dynamics of the active cells (both motile and multiplying), the passive cells(non-motile and non-growing) and nutrient concentration. We test the numerical behavior ofsuch models and compare them to relevant experimental data together with a criticalanalysis of the validity of the models based on recent observations of the swarmingbacteria which show that nutrients are not limitating but distinct subpopulations growingat different rates are likely present.

Keywords

Dendritic patternsBacillus subtilis swarmingReaction-diffusion equationsCell community growth.
Type
Research Article
Information
Mathematical Modelling of Natural Phenomena , Volume 5 , Issue 1: Cell migration , 2010 , pp. 148 - 162
Copyright
© EDP Sciences, 2010

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