The events driven by the financial crisis have highlighted limits and drawbacks of current paradigms. Economists began to rethink the role and impacts of financial factors and standard policies. At the same time, a more general sentiment of revision has challenged several consolidated “dogmas.” Accordingly, this special issue of Macroeconomic Dynamics aims to refresh the debate on some important macroeconomic topics from new and fresh perspectives. A number of questions relating to the challenges faced by macroeconomic theory and policies are raised. The issue, first, discusses some topics that stemmed from the financial factors, such as overleveraging, forward guidance, bank regulation; it then explores other “waters” related to price-setting behavior, productivity, and growth.