The Target Fabrication Facility (TFF) of an inertial fusion energy (IFE) power plant must supply about 500,000 targets per day. The target is injected into the target chamber at a rate of 5–10 Hz and tracked precisely so the heavy ion driver beams can be directed to the target. The feasibility of developing successful fabrication and injection methodologies at the low cost required for energy production (about $0.25/target, approximately 104 times less than current costs) is a critical issue for inertial fusion energy. A significant program is underway to develop the high-volume methods to supply economical IFE targets. This article reviews the requirements for heavy ion driven IFE target fabrication and injection, and presents the current status of and results from the development program. For the first time, an entire pathway from beginning to end is outlined for fabrication of a high-gain, distributed radiator target. A significant development and scale-up program will be necessary to implement this pathway for mass production of IFE targets.