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Appearance of a genetically-based pollution resistance in a marine gastropod, Nucella lapillus, in south-west Brittany: a new case of Dumpton syndrome

Published online by Cambridge University Press:  24 July 2008

M. Huet ,
N. Le Goïc  and
P.E. Gibbs
M. Huet*
Affiliation:
LEMAR, UMR CNRS 6539, Institut Universitaire Européen de la Mer, Université de Bretagne Occidentale, Place Copernic, F 29280 Plouzané
N. Le Goïc
Affiliation:
LEMAR, UMR CNRS 6539, Institut Universitaire Européen de la Mer, Université de Bretagne Occidentale, Place Copernic, F 29280 Plouzané
P.E. Gibbs
Affiliation:
Marine Biological Association of the UK, Citadel Hill, Plymouth PL1 2PB, UK
*
Correspondence should be addressed to: M. Huet, LEMAR, UMR CNRS 6539, Institut Universitaire Européen de la Mer, Université de Bretagne Occidentale, Place Copernic, F 29280 Plouzané email: [email protected]
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Abstract

Most neogastropod species exhibit masculinization of the female when subject to tributyltin (TBT) pollution (a process known as ‘imposex’). To date, the dog-whelk Nucella lapillus is seemingly unique in having a genetic deficiency (termed Dumpton syndrome or DS) that disrupts the development of normal male sex organs, its presence being readily recognizable by the underdevelopment, or non-development (aphally), of the penis, and incomplete formation (non-closure) of the vas deferens, causing a split prostate. In highly contaminated conditions, female carriers of DS can be identified by a lesser degree of masculinization (notably aphally): they escape sterilization caused by the advanced stages of imposex. To date, DS has only been reported in areas with high TBT pollution which induces sterilization of normal females (i.e. non DS-affected females). DS is now, for the first time, observed at some locations where present TBT levels are low and some normal females lack penis development. In such conditions it is not possible to discriminate normal from DS-affected females using aphally. As DS-affected females must be discarded from the calculation of the imposex bioindicators to monitor TBT pollution, indirect tools such as molecular probe are now needed to further survey those areas where DS and TBT pollution may interact as, for example, in south-west Brittany.

Keywords

Nucella lapilluspollution resistancetributyltinTBTtemporal evolutionimposex
Type
Research Article
Information
Journal of the Marine Biological Association of the United Kingdom , Volume 88 , Issue 7 , November 2008 , pp. 1475 - 1479
Copyright
Copyright © Marine Biological Association of the United Kingdom 2008

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References

REFERENCES

Barreiro, R., Quintela, M. and Ruiz, J.M. (1999) Aphally and imposex in Nucella lapillus from Galicia (NW Spain): incidence, geographical distribution and consequences for the biomonitoring of TBT contamination. Marine Ecology Progress Series 185, 229–238.CrossRefGoogle Scholar
Blaber, S.J.M. (1970) The occurrence of a penis-like outgrowth behind the right tentacle in spent females of Nucella lapillus (L.). Proceedings of the Malacological Society of London 39, 231–233.Google Scholar
Bryan, G.W., Gibbs, P.E. and Burt, G.R. (1988) A comparison of the effectiveness of tri-n-butyltin chloride and five other organotin compounds in promoting the development of imposex in dog-whelk, Nucella lapillus. Journal of the Marine Biological Association of the United Kingdom 68, 733–744.CrossRefGoogle Scholar
Bryan, G.W., Gibbs, P.E., Hummerstone, L.G. and Burt, G.R. (1986) The decline of the gastropod Nucella lapillus around south-west England: evidence for the effect of tributyltin from antifouling paints. Journal of the Marine Biological Association of the United Kingdom 66, 611–640.CrossRefGoogle Scholar
Colson, I. and Hughes, R.N. (2004) Rapid recovery of genetic diversity of dogwhelk (Nucella lapillus) populations after local extinction and recolonisation contradicts predictions from life-history characteristics. Molecular Ecology 13, 2223–2233.CrossRefGoogle Scholar
Gabe, M. (1968) Techniques histologiques. Paris: Ed Masson & Co, 1113 pp.Google Scholar
Gibbs, P.E. (1993) A male genital defect in the dog-whelk, Nucella lapillus (Neogastropoda), favouring the survival of a population in a TBT-polluted area. Journal of the Marine Biological Association of the United Kingdom 73, 667–678.CrossRefGoogle Scholar
Gibbs, P.E. (1999) Biological effects of contaminants: use of imposex in the dog-whelk (Nucella lapillus) as a bioindicator of tributyltin (TBT) pollution. ICES Techniques in Marine Environmental Sciences 24, 1–29.Google Scholar
Gibbs, P.E. (2005) Male genital defect (Dumpton syndrome) in the dog-whelk Nucella lapillus (Neogastropoda): Mendelian inheritance inferred, based on laboratory breeding experiments. Journal of the Marine Biological Association of the United Kingdom 85, 143–150.CrossRefGoogle Scholar
Gibbs, P.E., Bryan, G.W. and Pascoe, P.L. (1991) TBT-induced imposex in the dogwhelk, Nucella lapillus: geographical uniformity of the response and effects. Marine Environmental Research 32, 79–87.CrossRefGoogle Scholar
Gibbs, P.E., Bryan, G.W., Pascoe, P.L. and Burt, G.R. (1987) The use of the dog-whelk, Nucella lapillus, as an indicator of tributyltin (TBT) contamination. Journal of the Marine Biological Association of the United Kingdom 67, 507–523.CrossRefGoogle Scholar
Gibbs, P.E., Pascoe, P.L. and Burt, G.R. (1988) Sex change in the female dog-whelk, Nucella lapillus, induced by tributyltin from antifouling paints. Journal of the Marine Biological Association of the United Kingdom 68, 715–731.CrossRefGoogle Scholar
Huet, M., Paulet, Y.M. and Clavier, J. (2004) Imposex in Nucella lapillus: a ten year survey in NW Brittany. Marine Ecology Progress Series 270, 153–161.CrossRefGoogle Scholar
Huet, M., Paulet, Y.M. and Glémarec, M. (1996a) Tributyltin (TBT) pollution in the coastal waters of West Brittany as indicated by imposex in Nucella lapillus. Marine Environmental Research 41, 157–167.CrossRefGoogle Scholar
Huet, M., Paulet, Y.M. and Le Pennec, M. (1996b) Survival of Nucella lapillus in a tributyltin-polluted area in West Brittany: a further example of a male genital defect (Dumpton syndrome) favouring survival. Marine Biology 125, 543–549.CrossRefGoogle Scholar
Quintela, M., Barreiro, R. and Ruiz, J.M. (2002) Dumpton Syndrome reduces the tributyltin (TBT) sterilising effect on the development of the imposed vas deferens. Marine Environmental Research 54, 657–660.CrossRefGoogle ScholarPubMed
Smith, B.S. (1971) Sexuality in the American mud-snail Nassarius obsoletus Say. Proceedings of the Malacological Society of London 39, 377–378.Google Scholar
Smith, B.S. (1981) Tributyltin compounds induce male characteristics on female mud snails Nassarius obsoletus = Ilyanassa obsoletus. Journal of Applied Toxicology 1, 141–144.CrossRefGoogle ScholarPubMed