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Spatial Bias and Right Hemisphere Function: Sex-Specific Changes with Aging

Published online by Cambridge University Press:  15 February 2011

Peii Chen ,
Kelly M. Goedert ,
Elizabeth Murray ,
Karen Kelly ,
Shpresa Ahmeti  and
Anna M. Barrett
Peii Chen*
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey Department of Physical Medicine and Rehabilitation, the University of Medicine and Dentistry of New Jersey, Newark, New Jersey Graduate School of Biomedical Sciences, the University of Medicine and Dentistry of New Jersey, Newark, New Jersey
Kelly M. Goedert
Affiliation:
Department of Psychology, Seton Hall University, South Orange, New Jersey
Elizabeth Murray
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey
Karen Kelly
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey
Shpresa Ahmeti
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey
Anna M. Barrett
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey Department of Physical Medicine and Rehabilitation, the University of Medicine and Dentistry of New Jersey, Newark, New Jersey Graduate School of Biomedical Sciences, the University of Medicine and Dentistry of New Jersey, Newark, New Jersey Department of Neurology and Neurosciences, the University of Medicine and Dentistry of New Jersey, Newark, New Jersey Kessler Institute for Rehabilitation, West Orange, New Jersey
*
Correspondence and reprint requests to: Peii Chen, Kessler Foundation Research Center, 1199 Pleasant Valley Way, West Orange, NJ 07052. E-mail: [email protected]
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Abstract

Patterns of cerebral asymmetry related to visuospatial functions may change with age. The typical leftward bias on a line bisection task may reflect cerebral asymmetry. With age, such leftward bias decreases. This study demonstrated that the age-related decrease of leftward bias may actually be sex-specific. In addition, previous research suggests that young adults’ deviation in line bisection may reflect asymmetric hemispheric activation of perceptual–attentional “where” spatial systems, rather than motor-intentional “aiming” spatial systems; thus, we specifically fractionated “where” and “aiming” bias of men and women ranging in age from 22 to 93 years old. We observed that older men produced greater rightward line bisection errors, of primarily “where” spatial character. However, women's errors remained leftward biased, and did not significantly change with age. “Where” spatial systems may be linked to cortico-cortical processing networks involving the posterior part of the dorsal visuospatial processing stream. Thus, the current results are consistent with the conclusion that reduced right dorsal spatial activity in aging may occur in the male, but not female, adult spatial system development. (JINS, 2011, 17, 455–462)

Keywords

AttentionPerceptionAdult developmentHemispheric asymmetryPseudoneglectBrain lateralizationRight hemisphereAgingGender differences
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 17 , Issue 3 , May 2011 , pp. 455 - 462
Copyright
Copyright © The International Neuropsychological Society 2011

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