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Role of Reversal Learning Impairment in Social Disinhibition following Severe Traumatic Brain Injury

Published online by Cambridge University Press:  12 January 2016

Katherine Osborne-Crowley ,
Skye McDonald  and
Jacqueline A. Rushby
Katherine Osborne-Crowley*
Affiliation:
School of Psychology, The University of New South Wales, New South Wales, Australia
Skye McDonald
Affiliation:
School of Psychology, The University of New South Wales, New South Wales, Australia
Jacqueline A. Rushby
Affiliation:
School of Psychology, The University of New South Wales, New South Wales, Australia
*
Correspondence and reprint requests to: Katherine Osborne-Crowley, School of Psychology, The University of New South Wales, New South Wales, 2052, Australia. E-mail: [email protected]
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Abstract

Objectives: The current study aimed to determine whether reversal learning impairments and feedback-related negativity (FRN), reflecting reward prediction error signals generated by negative feedback during the reversal learning tasks, were associated with social disinhibition in a group of participants with traumatic brain injury (TBI). Methods: Number of reversal errors on a social and a non-social reversal learning task and FRN were examined for 21 participants with TBI and 21 control participants matched for age. Participants with TBI were also divided into low and high disinhibition groups based on rated videotaped interviews. Results: Participants with TBI made more reversal errors and produced smaller amplitude FRNs than controls. Furthermore, participants with TBI high on social disinhibition made more reversal errors on the social reversal learning task than did those low on social disinhibition. FRN amplitude was not related to disinhibition. Conclusions: These results suggest that impairment in the ability to update behavior when social reinforcement contingencies change plays a role in social disinhibition after TBI. Furthermore, the social reversal learning task used in this study may be a useful neuropsychological tool for detecting susceptibility to acquired social disinhibition following TBI. Finally, that the FRN amplitude was not associated with social disinhibition suggests that reward prediction error signals are not critical for behavioral adaptation in the social domain. (JINS, 2016, 21, 303–313)

Keywords

Brain injuriesSocial disinhibitionOrbitofrontal cortex (OFC)Reversal learningSocial reinforcementFeedback-related negativity (FRN)Reward prediction error
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 22 , Issue 3 , March 2016 , pp. 303 - 313
Copyright
Copyright © The International Neuropsychological Society 2016 

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