Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-22T19:00:09.976Z Has data issue: false hasContentIssue false
  • English
  • Français

Increased Cognitive Load Reveals Unilateral Neglect and Altitudinal Extinction in Chronic Stroke

Published online by Cambridge University Press:  21 May 2019

Michael Andres ,
Laurie Geers ,
Sophie Marnette ,
Françoise Coyette ,
Mario Bonato ,
Konstantinos Priftis  and
Nicolas Masson Open the ORCID record for Nicolas Masson [Opens in a new window]
Michael Andres*
Affiliation:
Psychological Sciences Research Institute, Université Catholique de Louvain, 1348, Louvain-la-Neuve, Belgium
Laurie Geers
Affiliation:
Psychological Sciences Research Institute, Université Catholique de Louvain, 1348, Louvain-la-Neuve, Belgium
Sophie Marnette
Affiliation:
Psychological Sciences Research Institute, Université Catholique de Louvain, 1348, Louvain-la-Neuve, Belgium
Françoise Coyette
Affiliation:
Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 1200, Brussels, Belgium
Mario Bonato
Affiliation:
Department of General Psychology, University of Padua, 35122 Padua, Italy
Konstantinos Priftis
Affiliation:
Department of General Psychology, University of Padua, 35122 Padua, Italy
Nicolas Masson*
Affiliation:
Psychological Sciences Research Institute, Université Catholique de Louvain, 1348, Louvain-la-Neuve, Belgium Department of Psychology, University of Tübingen, 72074, Tübingen, Germany
*
Correspondence and reprint requests to: Nicolas Masson, Place Cardinal Mercier, 10, 1348 Louvain-la-Neuve, Belgium. E-mail: [email protected]; or Michael Andres, E-mail: [email protected].
Correspondence and reprint requests to: Nicolas Masson, Place Cardinal Mercier, 10, 1348 Louvain-la-Neuve, Belgium. E-mail: [email protected]; or Michael Andres, E-mail: [email protected].
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective: Neuropsychological studies suggest that the ability to compensate for the presence of spatial neglect highly depends on the attentional resources a patient can rely on. The present research aimed to study neglect in situations where attentional resources are limited due to multitasking. Method: We examined two patients more than 3 years after a right-hemispheric stroke. Both had received neuropsychological rehabilitation for left neglect and did not show any impairment in standard tests. We used a dual-task paradigm combining a peripheral target detection task with a central shape recognition task. Peripheral targets could appear in left/right positions but also in lower/upper positions. Results: In patient #1, dual-task condition exacerbated left neglect and extinction. Patient #2 did not show any sign of neglect along the horizontal axis, but omitted half of the lower targets when they were presented simultaneously with upper targets under dual-task condition. This behavior reflects altitudinal extinction as the detection of single targets appearing either in upper or lower position was preserved. Conclusion: The present findings show that dual-tasking is a sensitive tool for the quantitative and qualitative assessment of spatial attention deficits, which are often overlooked by standard methods, especially in chronic stage. (JINS, 2019, 25, 644–653)

Keywords

Parietal lobestroke rehabilitationperceptual disordersneuropsychological testschronic brain damageattentional bias
Type
Case Report
Information
Journal of the International Neuropsychological Society , Volume 25 , Issue 6 , July 2019 , pp. 644 - 653
Copyright
Copyright © INS. Published by Cambridge University Press, 2019. 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Azouvi, P., Samuel, C., Louis-Dreyfus, A., Bernati, T., Bartolomeo, P., Beis, J.M., Chokron, S., Leclercq, M., Marchal, F., Martin, Y., de Montety, G., Olivier, S., Perennou, D., Pradat-Diehl, P., Prairial, C., Rode, G., Siéroff, E., & Wiart, L. (2002). Sensitivity of clinical and behavioural tests of spatial neglect after right hemisphere stroke. Journal of Neurology, Neurosurgery & Psychiatry, 73(2), 160–166. doi: 10.1136/jnnp.73.2.160 CrossRefGoogle ScholarPubMed
Becker, E. & Karnath, H.O. (2007). Incidence of visual extinction after left versus right hemisphere stroke. Stroke, 38(12), 3172–3174. doi: 10.1161/STROKEAHA.107.489096 CrossRefGoogle ScholarPubMed
Bickerton, W.L., Samson, D., Williamson, J., & Humphreys, G.W. (2011). Separating forms of neglect using the Apples Test: Validation and functional prediction in chronic and acute stroke. Neuropsychology, 25(5), 567. doi: 10.1037/a0023501 CrossRefGoogle ScholarPubMed
Blini, E., Romeo, Z., Spironelli, C., Pitteri, M., Meneghello, F., Bonato, M., & Zorzi, M. (2016). Multi-tasking uncovers right spatial neglect and extinction in chronic left-hemisphere stroke patients. Neuropsychologia, 92, 147–157. doi: 10.1016/j.neuropsychologia.2016.02.028 CrossRefGoogle ScholarPubMed
Bonato, M. (2015). Unveiling residual, spontaneous recovery from subtle hemispatial neglect three years after stroke. Frontiers in Human Neuroscience, 9, 413. doi: 10.3389/fnhum.2015.00413 CrossRefGoogle ScholarPubMed
Bonato, M. & Cutini, S. (2016). Increased attentional load moves the left to the right. Journal of Clinical and Experimental Neuropsychology, 38, 158–170. doi: 10.1080/13803395.2015.1091065 CrossRefGoogle ScholarPubMed
Bonato, M., Priftis, K., Marenzi, R., Umiltà, C., & Zorzi, M. (2010). Increased attentional demands impair contralesional space awareness following stroke. Neuropsychologia, 48(13), 3934–3940. doi: 10.1016/j.neuropsychologia.2010.08.022 CrossRefGoogle ScholarPubMed
Bonato, M., Priftis, K., Marenzi, R., Umiltà, C., & Zorzi, M. (2012). Deficits of contralesional awareness: A case study on what paper-and-pencil tests neglect. Neuropsychology, 26(1), 20. doi: 10.1037/a0025306 CrossRefGoogle ScholarPubMed
Bonato, M., Spironelli, C., Lisi, M., Priftis, K., & Zorzi, M. (2015). Effects of multimodal load on spatial monitoring as revealed by ERPs. PloS one, 10(9), e0136719. doi: 10.1371/journal.pone.0136719 CrossRefGoogle ScholarPubMed
Bowen, A., McKenna, K., & Tallis, R.C. (1999). Reasons for variability in the reported rate of occurrence of unilateral spatial neglect after stroke. Stroke, 30(6), 1196–1202. doi: 10.1161/01.STR.30.6.1196 CrossRefGoogle ScholarPubMed
Brown, J. (1958). Some tests of the decay theory of immediate memory. Quarterly Journal of Experimental Psychology, 10(1), 12–21. doi: 10.1080/17470215808416249 CrossRefGoogle Scholar
Butter, C.M., Evans, J., Kirsch, N., & Kewman, D. (1989). Altitudinal neglect following traumatic brain injury: A case report. Cortex, 25(1), 135–146. doi: 10.1016/S0010-9452(89)80013-9 CrossRefGoogle ScholarPubMed
Buxbaum, L.J., Ferraro, M.K., Veramonti, T., Farne, A., Whyte, J.M.D.P., Ladavas, E., Frassinetti, F., & Coslett, H.B. (2004). Hemispatial neglect subtypes, neuroanatomy, and disability. Neurology, 62(5), 749–756. doi: 10.1212/01.WNL.0000113730.73031.F4 CrossRefGoogle ScholarPubMed
Cassidy, T.P., Lewis, S., & Gray, C.S. (1998). Recovery from visuospatial neglect in stroke patients. Journal of Neurology, Neurosurgery & Psychiatry, 64(4), 555–557. doi: 10.1136/jnnp.64.4.555 CrossRefGoogle ScholarPubMed
Cherney, L.R. & Halper, A.S. (2001). Unilateral visual neglect in right-hemisphere stroke: A longitudinal study. Brain Injury, 15(7), 585–592. doi: 10.1080/02699050010009090 CrossRefGoogle ScholarPubMed
Corbetta, M. & Shulman, G.L. (2011). Spatial neglect and attention networks. Annual Review of Neuroscience, 34, 569–599. doi: 10.1146/annurev-neuro-061010-113731 CrossRefGoogle ScholarPubMed
Deouell, L.Y., Sacher, Y., & Soroker, N. (2005). Assessment of spatial attention after brain damage with a dynamic reaction time test. Journal of the International Neuropsychological Society, 11(6), 697–707. doi: 10.1017/S1355617705050824 CrossRefGoogle ScholarPubMed
Gauthier, L., Dehaut, F., & Joanette, Y. (1989). The Bells Test: A quantitative and qualitative test for visual neglect. International Journal of Clinical Neuropsychology, 11(2), 49–54.Google Scholar
Geurten, M., Vincent, E., Van der Linden, M., Coyette, F., & Meulemans, T. (2016). Working memory assessment: Construct validity of the Brown--Peterson Test. Canadian Journal of Behavioural Science, 48(4), 328–336. doi: 10.1037/cbs0000057 CrossRefGoogle Scholar
Glazer, H., Saadatpour, L., Doty, L., & Heilman, K.M. (2017). A case of posterior cortical atrophy with vertical neglect. Neurocase, 23(2), 114–119. doi: 10.1080/13554794.2017.1312692 CrossRefGoogle ScholarPubMed
Halligan, P.W., Marshall, J.C., & Wade, D.T. (1989). Visuospatial neglect: Underlying factors and test sensitivity. The Lancet, 334(8668), 908–911. doi: 10.1016/S0140-6736(89)91561-4 CrossRefGoogle Scholar
Husain, M. & Rorden, C. (2003). Non-spatially lateralized mechanisms in hemispatial neglect. Nature Reviews Neuroscience, 4(1), 26. doi: 10.1038/nrn1005 CrossRefGoogle ScholarPubMed
Karnath, H.O., Rennig, J., Johannsen, L., & Rorden, C. (2011). The anatomy underlying acute versus chronic spatial neglect: A longitudinal study. Brain, 134(3), 903–912. doi: 10.1093/brain/awq355 CrossRefGoogle ScholarPubMed
Karnath, H.O. & Rorden, C. (2012). The anatomy of spatial neglect. Neuropsychologia, 50(6), 1010–1017. doi: 10.1016/j.neuropsychologia.2011.06.027 CrossRefGoogle ScholarPubMed
List, A., Brooks, J.L., Esterman, M., Flevaris, A.V., Landau, A.N., Bowman, G., Stanton, V. Vanvleet, T.M., Robertson, L.C., & Schendel, K. (2008). Visual hemispatial neglect, re-assessed. Journal of the International Neuropsychological Society, 14(2), 243–256. doi: 10.1017/S1355617708080284 CrossRefGoogle ScholarPubMed
Mennemeier, M.S., Morris, M., & Heilman, K.M. (2004). Just thinking about targets can aggravate neglect on cancellation tests. Neurocase, 10(1), 29–38. doi: 10.1080/13554790490960468 CrossRefGoogle ScholarPubMed
Nijboer, T.C., Kollen, B.J., & Kwakkel, G. (2013). Time course of visuospatial neglect early after stroke: A longitudinal cohort study. Cortex, 49(8), 2021–2027. doi: 10.1016/j.cortex.2012.11.006 CrossRefGoogle ScholarPubMed
Peirce, J.W. (2007). PsychoPy—psychophysics software in Python. Journal of Neuroscience Methods, 162(1–2), 8–13. doi: 10.1016/j.jneumeth.2006.11.017 CrossRefGoogle ScholarPubMed
Peterson, L. & Peterson, M.J. (1959). Short-term retention of individual verbal items. Journal of Experimental Psychology, 58(3), 193. doi: 10.1037/h0049234 CrossRefGoogle ScholarPubMed
Pitzalis, S., Spinelli, D., & Zoccolotti, P. (1997). Vertical neglect: Behavioral and electrophysiological data. Cortex, 33(4), 679–688.CrossRefGoogle ScholarPubMed
Rapcsak, S.Z., Cimino, C.R., & Heilman, K.H. (1988). Altitudinal neglect. Neurology, 38, 277–281. doi: 10.1212/WNL.38.2.277 CrossRefGoogle ScholarPubMed
Rengachary, J., d’Avossa, G., Sapir, A., Shulman, G.L., & Corbetta, M. (2009). Is the Posner reaction time test more accurate than clinical tests in detecting left neglect in acute and chronic stroke?. Archives of Physical Medicine and Rehabilitation, 90(12), 2081–2088. doi: 10.1016/j.apmr.2009.07.014 CrossRefGoogle ScholarPubMed
Ricci, R. & Chatterjee, A. (2004). Sensory and response contributions to visual awareness in extinction. Experimental Brain Research, 157(1), 85–93. doi: 10.1007/s00221-003-1823-8 CrossRefGoogle ScholarPubMed
Ricci, R., Genero, R., Colombatti, S., Zampieri, D., & Chatterjee, A. (2005). Visuomotor links in awareness: evidence from extinction. Neuroreport, 16(8), 843–847.CrossRefGoogle Scholar
Ricci, R., Salatino, A., Garbarini, F., Ronga, I., Genero, R., Berti, A., & Neppi-Mòdona, M. (2016). Effects of attentional and cognitive variables on unilateral spatial neglect. Neuropsychologia, 92, 158–166. doi: 10.1016/j.neuropsychologia.2016.05.004 CrossRefGoogle ScholarPubMed
Robertson, I.H., Frasca, R., 1992. Attentional load and visual neglect. International Journal of Neuroscience, 62, 45–56. doi: 10.3109/00207459108999756 CrossRefGoogle ScholarPubMed
Schenkenberg, T., Bradford, D.C., & Ajax, E.T. (1980). Line bisection and unilateral visual neglect in patients with neurologic impairment. Neurology, 30(5), 509–509. doi: 10.1212/WNL.30.5.509 CrossRefGoogle ScholarPubMed
Shelton, P.A., Bowers, D., & Heilman, K.H. (1990). Peripersonal and vertical neglect. Brain, 113, 191–205. doi: 10.1093/brain/113.1.191 CrossRefGoogle ScholarPubMed
van Dijck, J.P., Abrahamse, E.L., Majerus, S., & Fias, W. (2013). Spatial attention interacts with serial-order retrieval from verbal working memory. Psychological Science, 24(9), 1854–1859. doi: 10.1177/0956797613479610 CrossRefGoogle ScholarPubMed
Ventre, J., Flandrin, J.M., & Jeannerod, M. (1984). In search for the egocentric reference. A neurophysiological hypothesis. Neuropsychologia, 22(6), 797–806. doi: 10.1016/0028-3932(84)90104-0 CrossRefGoogle ScholarPubMed
Supplementary material: File

Andres et al. supplementary material

Andres et al. supplementary material 1

Download Andres et al. supplementary material(File)
File 27.8 KB