Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-22T20:36:07.676Z Has data issue: false hasContentIssue false
  • English
  • Français

Evidence for the Solidarity of the Expressive and Receptive Language Systems: A Retrospective Study

Published online by Cambridge University Press:  10 November 2010

Dana C. Moser ,
Andrew C. Papanicolaou ,
Paul Swank  and
Joshua I. Breier
Dana C. Moser
Affiliation:
Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas
Andrew C. Papanicolaou*
Affiliation:
Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas
Paul Swank
Affiliation:
Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas
Joshua I. Breier
Affiliation:
Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas
*
Correspondence and reprint requests to: Andrew C. Papanicolaou, Center for Clinical Neurosciences, University of Texas Health Science Center at Houston, 1333 Moursund Street, Ste. H 114, Houston, TX 77030. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

A strong tendency toward left hemisphere (LH) language dominance has been well established, as evidenced by the high prevalence of language impairment following sudden onset lesions in the LH. In the presence of progressive LH pathology, such as epilepsy, substantial deviations in language organization can occur. However, the question regarding whether reorganization involves both expressive and receptive language functions or only the one directly affected by the primary location of pathology has not been settled. Using Wada testing scores from 296 epilepsy patients and estimated rates of typical dominance in the normal population, we assessed the frequency with which left frontal and temporal pathology resulted in reorganization of only the expressive or receptive language function or both. The comparisons revealed: (1) a significantly higher prevalence of atypical organization (i.e., deviations from LH dominance) among the LH patients compared to normal population estimates and right hemisphere patients, and (2) that regardless of pathology location within the LH, the rates of atypical reorganization for both expressive and receptive language were essentially equal. These results constitute evidence that the two language functions are intimately yoked and that when disruption to the system results in reorganization, it usually yields functional changes throughout the system. (JINS, 2010, 17, 000–000)

Keywords

Brain plasticityEpilepsyFunctional reorganizationHandednessHemispheric dominanceWada procedure
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 17 , Issue 1 , January 2011 , pp. 62 - 68
Copyright
Copyright © The International Neuropsychological Society 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bryden, M.P., Hécaen, H., DeAgostini, M. (1983). Patterns of cerebral organization. Brain and Language, 20, 249–262.CrossRefGoogle ScholarPubMed
Gaillard, W.D., Berl, M.M., Moore, E.N., Ritzl, E.K., Rosenberger, L.R., Weinstein, S.L., Theodore, W.H. (2007). Atypical language in lesional and nonlesional complex partial epilepsy. Neurology, 69, 1761–1771.CrossRefGoogle ScholarPubMed
Geschwind, N. (1970). The organization of language and the brain. Science, 170, 940–944.CrossRefGoogle ScholarPubMed
Kamada, K., Sawamura, Y., Takeuchi, F., Kuriki, S., Kawai, K., Morita, A., Todo, T. (2007). Expressive and receptive language areas determined by a non-invasive reliable method using functional magnetic resonance imaging and magnetoencephalography. Neurosurgery, 60, 296–306.CrossRefGoogle ScholarPubMed
Kamada, K., Takeuchi, F., Kuriki, S., Todo, T., Morita, A., Sawamura, Y. (2006). Dissociated expressive and receptive language functions on magnetoencephalography, functional magnetic resonance imaging, and amobarbital studies. Case report and review of the literature. Journal of Neurosurgery, 104, 598–607.CrossRefGoogle ScholarPubMed
Knecht, S., Deppe, M., Dräger, B., Bobe, L., Lohmann, H., Ringelstein, E., Henningsen, H. (2000). Language lateralization in healthy right-handers. Brain, 123(Pt 1), 74–81.CrossRefGoogle ScholarPubMed
Kurthen, M., Helmstaedter, C., Linke, D.B., Hufnagel, A., Elger, C.E., Schramm, J. (1994). Quantitative and qualitative evaluation of patterns of cerebral language dominance. An amobarbital study. Brain and Language, 46, 536–564.CrossRefGoogle ScholarPubMed
Kurthen, M., Helmstaedter, C., Linke, D.B., Solymosi, L., Elger, C.E., Schramm, J. (1992). Interhemispheric dissociation of expressive and receptive language functions in patients with complex-partial seizures: An amobarbital study. Brain and Language, 43, 694–712.CrossRefGoogle ScholarPubMed
Lee, D., Swanson, S.J., Sabsevitz, D.S., Hammeke, T.A., Scott Winstanley, F., Possing, E.T., Binder, J.R. (2008). Functional MRI and Wada studies in patients with interhemispheric dissociation of language functions. Epilepsy & Behavior, 13, 350–356.CrossRefGoogle ScholarPubMed
Maestú, F., Saldaña, C., Amo, C., González-Hidalgo, M., Fernandez, A., Fernandez, S., Ortiz, T. (2004). Can small lesions induce language reorganization as large lesions do? Brain and Language, 89, 433–438.CrossRefGoogle Scholar
Newcombe, F., Ratcliff, G. (1973). Handedness, speech lateralization and ability. Neuropsychologia, 11, 399–407.CrossRefGoogle ScholarPubMed
Papanicolaou, A.C., Simos, P.G., Breier, J.I., Zouridakis, G., Wilmore, L.J., Wheless, J.W., Gormley, W.B. (1999). Magnetoencephalographic mapping of the language specific cortex. Journal of Neurosurgery, 90, 85–93.CrossRefGoogle ScholarPubMed
Pataraia, E., Simos, P.G., Castillo, E.M., Billingsley-Marshall, R.L., McGregor, A.L., Breier, J.I., Papanicolaou, A.C. (2004). Reorganization of language-specific cortex in patients with lesions or mesial temporal epilepsy. Neurology, 63, 1825–1832.CrossRefGoogle ScholarPubMed
Pedersen, P.M., Jørgensen, H.S., Nakayama, H., Raaschou, H.O., Olsen, T.S. (1995). Aphasia in acute stroke: Incidence, determinants, and recovery. Annals of Neurology, 38, 659–666.CrossRefGoogle ScholarPubMed
Pujol, J., Deus, J., Losilla, J.M., Capdevila, A. (1999). Cerebral lateralization of language in normal left-handed people studied by functional MRI. Neurology, 52, 1038–1043.CrossRefGoogle ScholarPubMed
Rasmussen, T., Milner, B. (1977). The role of early left-brain injury in determining lateralization of cerebral speech functions. Annals of the New York Academy of Sciences, 299, 355–369.CrossRefGoogle ScholarPubMed
Risse, G.L., Gates, J.R., Fangman, M.C. (1997). A reconsideration of bilateral language representation based on the intracarotid amobarbital procedure. Brain and Cognition, 33, 118–132.CrossRefGoogle ScholarPubMed
Rutten, G.J., Ramsey, N.F., van Rijen, P.C., Alpherts, W.C., van Veelen, C.W. (2002). FMRI-determined language lateralization in patients with unilateral or mixed language dominance according to the Wada test. Neuroimage, 17, 447–460.CrossRefGoogle ScholarPubMed
Springer, J.A., Binder, J.R., Hammeke, T.A., Swanson, S.J., Frost, J.A., Bellgowan, P.S.F., Mueller, W.M. (1999). Language dominance in neurologically normal and epilepsy subjects: A functional MRI study. Brain, 122, 2033–2045.CrossRefGoogle ScholarPubMed
Vikingstad, E.M., George, K.P., Johnson, A.F., Cao, Y. (2000). Cortical language lateralization in right handed normal subjects using functional magnetic resonance imaging. Journal of Neurological Sciences, 175, 17–27.CrossRefGoogle ScholarPubMed