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Effect of asymptomatic carotid artery disease on cognitive outcome after cardiopulmonary bypass

Published online by Cambridge University Press:  26 February 2009

Guy Vingerhoets ,
Guido van Nooten  and
Constantin Jannes
Guy Vingerhoets
Affiliation:
Department of Psychiatry and Neuropsychology, University Gent
Guido van Nooten
Affiliation:
Center for Cardiac Surgery, University Gent
Constantin Jannes
Affiliation:
Department of Psychiatry and Neuropsychology, University Gent
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Abstract

This prospective study reinvestigates the effect of asymptomatic carotid artery disease on the cognitive outcome after cardiopulmonary bypass (CPB) (Harrison et al., 1989). Patients (N = 104) scheduled for cardiac surgery using CPB were classified in one of two groups based on the results of a preoperative duplex B mode Dopplcr scan of the internal carotid arteries. All patients received a neuropsychological examination before surgery, 8 days after surgery, and 6 months after surgery (n = 79). When group data are considered, patients showed evidence of selective cognitive dysfunction early after surgery. These dysfunctions were resolved by the sixth postoperative month. We found no indications that the presence of asymptomatic carotid artery disease increased the incidence of cognitive disturbances after CPB or differentially affected the postoperative performance. We conclude that mild to moderate asymptomatic carotid artery disease does not appear to play a major role in the genesis of postoperative neuropsychological sequelae. (JINS, 1996,2, 236–239.)

Keywords

Asymptomatic carotid artery diseaseNeuropsychologyCardiopulmonary bypassExtracorporeal circulation
Type
Research Article
Information
Journal of the International Neuropsychological Society , Volume 2 , Issue 3 , May 1996 , pp. 236 - 239
Copyright
Copyright © The International Neuropsychological Society 1996

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References

REFERENCES

Brcener, B.J., Brief, D.K., & Alpert, J. (1987). The risk of stroke in patients with asymptomatic carotid stenosis undergoing cardiac surgery: A follow-up study. Journal of Vascular Surgery, 5, 269–279.CrossRefGoogle Scholar
Hammekc, T.A. & Hastings, J.E. (1988). Neuropsychologic alterations after cardiac operation. Journal of Thoracic and Cardiovascular Surgery, 96, 326–331.CrossRefGoogle Scholar
Harrison, M.J. (1993). The potential role of carotid artery disease. In Smith, P. & Taylor, K. (Eds.), Cardiac surgery and the brain (pp. 17–23). London: Edward Arnold.Google Scholar
Harrison, M.J.G., Schneidau, A., Ho, R., Smith, P.L.C., Newman, S., & Treasure, T. (1989). Cerebrovascular disease and functional outcome after coronary artery bypass surgery. Stroke, 20, 235–2371.CrossRefGoogle ScholarPubMed
Klonoff, H., Clark, C., Kavanagh-Gray, D., Mizgala, H., & Mun-ro, I. (1989). Two-year follow-up study of coronary bypass surgery. Journal of Thoracic and Cardiovascular Surgery, 97, 78–85.CrossRefGoogle ScholarPubMed
Lezak, M.D. (1983). Neuropsychological assessment (2nd ed.). New York: Oxford Press.Google Scholar
Newman, S. (1989). The incidence and nature of neuropsychological morbidity following cardiac surgery. Perfusion, 4, 93–100.CrossRefGoogle Scholar
Schell, R.M., Kern, F.H., Greeley, W.J., Schulman, S.R., Frasco, P.E., Croughwell, N.D., Newman, M., & Reves, J.G. (1993). Cerebral blood flow and metabolism during cardiopulmonary bypass. Anesthesia & Analgesia, 76, 849–865.CrossRefGoogle ScholarPubMed
Shaw, P.J., Bates, D., Cartlidge, N.E.F., French, J.M., Heaviside, D., Julian, D., & Shaw, D.A. (1987). Long-term intellectual dysfunction following coronary artery bypass graft surgery: A six-month follow-up study. Quarterly Journal of Medicine, 62, 259–268.Google ScholarPubMed
Strandncss, D.E. (1993). Duplex scanning in vascular disorders (2nd ed.). New York: Raven Press.Google Scholar
Van Brcukelen, G.J.P. & Souren, D.A.P.B. (1990). Een eenvoudig model en een concentratiescore voor Bourdon tests [A simple model and concentration score for Bourdon tests]. Nederlands Tijdschrift voor de Psychologic, 45, 40–45.Google Scholar
Vingerhoets, G., De Soete, G., & Jannes, C. (1995). Relationship between emotional variables and cognitive test performance before and after open-heart surgery. The Clinical Neuropsychologist, 9, 198–202.CrossRefGoogle Scholar