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Retrograde amnesia for semantic information in Alzheimer's disease

Published online by Cambridge University Press:  28 January 2005

MARTIJN MEETER ,
ARIANE KOLLEN  and
PHILIP SCHELTENS
MARTIJN MEETER
Affiliation:
Department of Cognitive Psychology, Vrije Universiteit Amsterdam, The Netherlands
ARIANE KOLLEN
Affiliation:
De Geestgronden IGG, Bennebroek, The Netherlands
PHILIP SCHELTENS
Affiliation:
Department Neurology, Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
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Abstract

Patients with mild to moderate Alzheimer's disease and normal controls were tested on a retrograde amnesia test with semantic content (Neologism and Vocabulary Test, or NVT), consisting of neologisms to be defined. Patients showed a decrement as compared to normal controls, pointing to retrograde amnesia within semantic memory. No evidence for a gradient within this amnesia was found, although one was present on an autobiographic test of retrograde amnesia that had a wider time scale. Several explanations for these results are presented, including one that suggests that extended retrograde amnesia and semantic memory deficits are in fact one and the same deficit. (JINS, 2005, 11, 40–48.)

Keywords

Semantic memoryVocabularyNeologismsAutobiographic memoryAlzheimer's disease
Type
Research Article
Information
Journal of the International Neuropsychological Society , Volume 11 , Issue 1 , January 2005 , pp. 40 - 48
Copyright
© 2005 The International Neuropsychological Society

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References

REFERENCES

APA. (1994). Diagnostic and Statistical Manual IV. Washington DC: American Psychiatric Association.
Bahrick, H.P. (1984). Semantic memory content in permastore: Fifty years of memory for Spanish learned in school. Journal of Experimental Psychology: General, 113, 1–27.Google Scholar
Bahrick, H.P. (1992). Stabilized memory of unrehearsed knowledge. Journal of Experimental Psychology: General, 121, 112–113.Google Scholar
Beatty, W.W. & Salmon, D.P. (1991). Remote memory for visuospatial information in patients with Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology, 4, 14–17.Google Scholar
Beatty, W.W., Salmon, D.P., Butters, N., Heindel, W.C., & Granholm, E.L. (1988). Retrograde amnesia in patients with Alzheimer's disease or Huntington's disease. Neuropsychology of Aging, 9, 181–186.Google Scholar
Brandt, J. & Rich, J.B. (1995). Memory disorders in the dementias. In A.D. Baddeley, B.A. Wilson, & F.N. Watts (Eds.), Handbook of memory disorders (pp. 243–270). Chichester (UK): Wiley & Sons.
Bright, P., Jaldow, E., & Kopelman, M.D. (2002). The National Adult Reading Test as a measure of premorbid intelligence: A comparison with estimates derived from demographic variables. Journal of the International Neuropsychological Society, 8, 847–854.Google Scholar
Brown, A.S. (2002). Consolidation theory and retrograde amnesia in humans. Psychonomic Bulletin & Review, 9, 403–425.Google Scholar
Cahn, D.A., Salmon, D.P., Butters, N., Wiederholt, W.C., Corey-Bloom, J., Edelstein, S.L., & Barrett-Conner, E. (1995). Detection of dementia of the Alzheimer type in a population-based sample: Neuropsychological test performance. Journal of the International Neuropsychological Society, 1, 252–260.Google Scholar
Cermak, L.S. (1984). The episodic/semantic distinction in amnesia. In L.R. Squire & N. Butters (Eds.), The neuropsychology of memory (pp. 55–62). New York: Guilford Press.
Cockburn, J., Keene, J., Hope, T., & Smith, P. (2000). Progressive decline in NART score with increasing dementia severity. Journal of Clinical and Experimental Neuropsychology, 22, 508–517.Google Scholar
Conway, M.A., Cohen, G., & Stanhope, N. (1991). On the very long term retention of knowledge acquired through formal education: Twelve years of cognitive psychology. Journal of Experimental Psychology: General, 120, 395–409.Google Scholar
Deelman, B.G., Koning-Haanstra, M., Liebrand, W.B.G., & van der Burg, W. (1981). Een afasie-test voor auditief taalbegrip en mondeling taalgebruik. Handleiding. Lisse, The Netherlands: Swets & Zeitlinger.
Deweer, B., Pillon, B., Pochon, J.B., & Dubois, B. (2001). Is the HM story only a ‘remote memory’? Some facts about the hippocampus and memory in humans. Behavioural Brain Research, 127, 209–224.Google Scholar
de Wilde, E.F. (2001). De ontwikkeling van een test om retrograde amnesie voor semantische informatie te kunnen inventariseren [Development of a test to measure retrograde amnesia for semantic information], Afd.Psychologie. Amsterdam: University of Amsterdam, Dept. of Psychology.
Folstein, M.F., Folstein, S.E., & McHugh, P.R. (1975). Mini mental state. Journal of Psychiatric Research, 12, 189–198.Google Scholar
Garrard, P., Perry, R., & Hodges, J.R. (1997). Disorders of semantic memory. Journal of Neurology, Neurosurgery and Psychiatry, 62, 431–435.Google Scholar
Graham, K.S. & Hodges, J.R. (1997). Differentiating the roles of the hippocampal complex and the neocortex in long-term memory storage: Evidence from the study of semantic dementia and Alzheimer's disease. Neuropsychology, 11, 77–89.Google Scholar
Graham, K.S., Simons, J.S., Pratt, K.H., Patterson, K., & Hodges, J.R. (2000). Insights from semantic dementia on the relationship between episodic and semantic memory. Neuropsychologia, 38, 313–324.Google Scholar
Hayes, S., Ryan, L., Nadel, L., Perschler, P., & Spitler, K. (2001). A Comparison of fMRI Hippocampal Activation during Semantic and Episodic Retrieval using a Category Production Task (Poster). San Diego, CA: Society for Neuroscience.
Heslinga, H., van der Burg, W., & Saan, R.J. (1983). Het coderen van het opleidingsniveau [The coding of level of educational attainment]: Section Neuropsychology, Groningen University.
Hodges, J.R., Patterson, K., Oxbury, S., & Funnell, E. (1992). Semantic dementia: Progressive fluent aphasia with temporal lobe atrophy. Brain, 115, 1783–1806.Google Scholar
Kapur, N., Thompson, P., Karsounis, L.D., & Abbott, P. (1998). Retrograde amnesia: Clinical and methodological caveats. Neuropsychologia, 37, 27–30.Google Scholar
Kazui, H., Hashimoto, M., Hirono, N., & Mori, E. (2003). Nature of personal semantic memory: Evidence from Alzheimer's disease. Neuropsychologia, 41, 981–988.Google Scholar
Kim, J.J. & Fanselow, M.S. (1992). Modality-specific retrograde amnesia for fear. Science, 256, 675–677.Google Scholar
Kopelman, M.D., Wilson, B.A., & Baddeley, A.D. (1989). The autobiographical memory interview: A new assessment of autobiographical and personal semantic memory in amnesic patients. Journal of Clinical and Experimental Psychology, 11, 724–744.Google Scholar
Kopelman, M.D., Wilson, B., & Baddeley, A.D. (1990). The autobiographical memory interview. Bury St. Edmunds (UK): Thames Valley Test Company.
Lambon Ralph, M.A., Powell, J., Howard, D., Whitworth, A.B., Garrard, P., & Hodges, J.R. (2001). Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: A comparative neuropsychological study and literature review. Journal of Neurology, Neurosurgery, and Psychiatry, 70, 149–156.Google Scholar
Leplow, B., Dierks, C., Herrmann, P., Pieper, N., Annecke, R., & Ulm, G. (1997). Remote memory in Parkinson's disease and senile dementia. Neuropsychologia, 35, 547–557.Google Scholar
Lezak, M.D. (1995). Neuropsychological assessment (3rd ed.). Oxford: Oxford University Press.
Lindeboom, J. & Jonker, C. (1989). Amsterdamse dementie screeningstest. Lisse, The Netherlands: Swets & Zeitlinger.
Luria, A.R. (1966). Human brain and psychological processes. New York: Harper & Row.
McKhann, G., Drachman, D., Folstein, M.F., Katzman, R., Price, D., & Stadlan, E.M. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34, 939–944.Google Scholar
Meeter, M. & de Wilde, E.F. (2001). Neologismen- en Vocabulairetest. Amsterdam: University of Amsterdam, Dept. of Psychology (available at www.neuromod.org/publications).
Meeter, M. & Murre, J.M.J. (2003). Autobiografisch Geheugeninterview. Dutch adaptation of the autobiographical memory interview (Internal report). Amsterdam, The Netherlands: Universiteit van Amsterdam.
Meeter, M. & Murre, J.M.J. (2004). Consolidation of long-term memory: Evidence and alternatives. Psychological Bulletin, 130, 843–857.Google Scholar
Moscovitch, M. (1982). Multiple dissociations of function in amnesia. In L.S. Cermak (Ed.), Human memory and amnesia (pp. 337–370). Hillsdale, New Jersey: Lawrence Erlbaum.
Nelson, H.E. & O'Connell, A. (1978). Dementia: The estimation of premorbid intelligence levels using the New Adult Reading Test. Cortex, 14, 234–244.Google Scholar
Petersen, R.C., Smith, G.E., Waring, S.C., Ivnik, R.J., Tangalos, E.G., & Kokmen, E. (1999). Mild cognitive impairment. Clinical characterization and outcome. Archives of Neurology, 56, 303–308.Google Scholar
Ribot, T. (1881). Les maladies de la memoire. Paris, France: Germer Baillare.
Rosenbaum, R.S., Winocur, G., & Moscovitch, M. (2001). New views on old memories: Re-evaluating the role of the hippocampal complex. Behavioural Brain Research, 127, 183–197.Google Scholar
Salmon, D.P., Heindel, W.C., & Butters, N. (1992). Semantic memory, priming and skill learning in Alzheimer's disease. In L. Backman (Ed.), Memory function in dementia (pp. 99–118). Amsterdam, The Netherlands: Elsevier.
Schmand, B. (1997). Aanvulling op de 8-woordentest van de Amstedamse Dementie Screening (ADS-6) (Internal report): Slotervaartziekenhuis, Amsterdam, The Netherlands.
Schmand, B., Geerlings, M.I., Jonker, C., & Lindeboom, J. (1998). Reading ability as an estimator of premorbid intelligence: Does it remain stable in emergent dementia? Journal of Clinical and Experimental Neuropsychology, 20, 42–51.Google Scholar
Snowden, J.S., Griffiths, H., & Neary, D. (1996). Semantic-episodic memory interactions in semantic dementia: Implications for retrograde memory function. Cognitive Neuropsychology, 13, 1101–1137.Google Scholar
Spaan, P.E.J. (2003). Early assessment of dementia: The contributions of different memory components. Afd. Psychologie. Amsterdam, The Netherlands: Universiteit van Amsterdam.
Spaan, P.E.J., Raaijmakers, J.G.W., & Jonker, C. (2003). Alzheimer's disease versus normal ageing: A review of the efficiency of clinical and experimental memory measures. Journal of Clinical and Experimental Neuropsychology, 25, 216–233.Google Scholar
Squire, L.R. (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psychological Review, 99, 195–231.Google Scholar
Squire, L.R. & Zola, S.M. (1998). Episodic memory, semantic memory, and amnesia. Hippocampus, 8, 205–211.Google Scholar
Thompson, S.A., Graham, K.S., Patterson, K., Shahakian, B.J., & Hodges, J.R. (2002). Is knowledge of famous people disproportionately impaired in patients with early and questionable Alzheimer's disease. Neuropsychology, 16, 344–358.Google Scholar
Vargha-Khadem, F., Gadian, D.G., Watkins, K.E., Connelly, A., Paesschen, W.V., & Mishkin, M. (1997). Differential effects of early hippocampal pathology on episodic and semantic memory. Science, 277, 376–390.Google Scholar
Verfaellie, M., Reiss, L., & Roth, H.L. (1995). Knowledge of new English vocabulary in amnesia: An examination of premorbidly acquired semantic memory. Journal of the International Neuropsychological Society, 1, 443–453.Google Scholar
Westmacott, R., Leach, L., Freedman, M., & Moscovitch, M. (2001). Different patterns of autobiographical memory loss in semantic dementia and medial temporal lobe amnesia: A challenge to consolidation theory. Neurocase, 7, 37–55.Google Scholar
Wilson, R.S., Kasniak, A.W., & Fox, J.H. (1981). Remote memory in senile dementia. Cortex, 17, 41–48.Google Scholar