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Occurrence and Recovery of Different Neglect-Related Symptoms in Right Hemisphere Infarct Patients during a 1-Year Follow-Up

Published online by Cambridge University Press:  03 April 2018

Laura Nurmi*
Affiliation:
Faculty of Social Sciences, Psychology, University of Tampere, Tampere, Finland
Eija-Inkeri Ruuskanen
Affiliation:
Faculty of Social Sciences, Psychology, University of Tampere, Tampere, Finland
Mari Nurmi
Affiliation:
Faculty of Social Sciences, Psychology, University of Tampere, Tampere, Finland
Anna-Maija Koivisto
Affiliation:
Faculty of Social Sciences, Health Sciences, University of Tampere, Tampere, Finland
Anna-Kaisa Parkkila
Affiliation:
Department of Neurology and Rehabilitation, Tampere University Hospital, Tampere, Finland
Heikki Numminen
Affiliation:
Department of Neurology and Rehabilitation, Tampere University Hospital, Tampere, Finland
Prasun Dastidar
Affiliation:
Department of Radiology, Tampere University Hospital, Tampere, Finland
Mervi Jehkonen
Affiliation:
Faculty of Social Sciences, Psychology, University of Tampere, Tampere, Finland
*
Correspondence and reprint requests to: Laura Nurmi, University of Tampere, Faculty of Social Sciences, Psychology, FIN-33014 University of Tampere, Finland. E-mail: [email protected]

Abstract

Objectives: To examine the occurrence of and recovery from visual neglect-related symptoms with the focus on neglect laterality, ipsilateral orienting bias, and slowed processing speed in right hemisphere (RH) infarct patients during a 1-year follow-up. Furthermore, to propose guidelines for assessing processing speed alongside the Behavioural Inattention Test (BIT). Methods: We studied three RH patient groups: neglect (N+), mild left inattention (MLI+), and non-neglect (N−) patients, and healthy controls. The BIT with some additional analyses was conducted at the acute phase and at 6 and 12 months. Results: The N+ group’s BIT score increased and originally lateralized omissions became more evenly distributed during the follow-up. The N+ and MLI+ groups’ starting points were more rightward located than the healthy group’s at the acute phase and at 6, and partly at 12 months. Patient groups were slower than the controls in performing cancellation tests at the acute phase. The N+ and MLI+ groups remained slower than the controls throughout the follow-up. Conclusions: During the first year after RH infarct, originally left-sided manifestation of neglect shifted toward milder non-lateralized attentional deficit. Ipsilateral orienting bias and slowed processing speed appeared to be rather persistent neglect-related symptoms both in neglect patients and patients with initially milder inattention. We propose some effortless, tentative ways of examining processing speed and ipsilateral orienting bias alongside the BIT to better recognize these neglect-related symptoms, and highlight the need to assess and treat patients with initially milder inattention, who have been under-recognized and under-treated in clinical work. (JINS, 2018, 24, 617–628)

Type
Regular Research
Copyright
Copyright © The International Neuropsychological Society 2018 

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References

REFERENCES

Adair, J.C., & Barrett, A.M. (2008). Spatial neglect clinical and neuroscience review: A wealth of information on the poverty of attention. Annals of the New York Academy of Sciences, 1142, 2143.CrossRefGoogle Scholar
Azouvi, P., Bartolomeo, P., Beis, J.M., Perennou, D., Pradat-Diehl, P., & Rousseaux, M. (2006). A battery of tests for the quantitative assessment of unilateral neglect. Restorative Neurology and Neuroscience, 24, 273285.Google Scholar
Azouvi, P., Samuel, C., Louis-Dreyfus, A., Bernati, T., Bartolomeo, P., Beis, J.M., & Rousseaux, M. (2002). Sensitivity of clinical and behavioural tests of spatial neglect after right hemisphere stroke. Journal of Neurology, Neurosurgery, and Psychiatry, 73, 160166.CrossRefGoogle ScholarPubMed
Bartolomeo, P. (1997). The novelty effect in recovered hemineglect. Cortex, 33, 323332.CrossRefGoogle ScholarPubMed
Bartolomeo, P., & Chokron, S. (1999). Left unilateral neglect or right hyperattention? Neurology, 53, 20232027.CrossRefGoogle ScholarPubMed
Bartolomeo, P., & Chokron, S. (2002). Orienting of attention in left unilateral neglect. Neuroscience and Biobehavioral Reviews, 262, 217234.Google Scholar
Behrmann, M., & Meegan, D.V. (1998). Visuomotor processing in unilateral neglect. Consciousness and Cognition, 7, 381409.CrossRefGoogle ScholarPubMed
Benton, A. (1986). Reaction time in brain disease: Some reflections. Cortex, 22, 129140.CrossRefGoogle ScholarPubMed
Binder, J., Marshall, R., Lazar, R., Benjamin, J., & Mohr, J.P. (1992). Distinct syndromes of hemineglect. Archives of Neurology, 49, 11871194.Google Scholar
Bonato, M. (2012). Neglect and extinction depend greatly on task demands: A review. Frontiers in Human Neuroscience, 6, 195.CrossRefGoogle ScholarPubMed
Butler, B.C., Lawrence, M., Eskes, G.A., & Klein, R. (2009). Visual search patterns in neglect: Comparisons of peripersonal and extrapersonal space. Neuropsychologia, 47, 869878.Google Scholar
Buxbaum, L.J., Ferraro, M.K., Veramonti, T., Farne, A., Whyte, J., Lavadas, E., Frassinetti, F., && Coslett, H.B. (2004). Hemispatial neglect subtypes, neuroanatomy, and disability. Neurology, 62, 749756.Google Scholar
Cassidy, T.P., Lewis, S., & Grey, C.S. (1998). Recovery from visuospatial neglect in stroke patients. Journal of Neurology, Neurosurgery, and Psychiatry, 64, 555557.CrossRefGoogle ScholarPubMed
Chen, P., Hreha, K., Kong, Y., & Barrett, A.M. (2015). Impact of spatial neglect on stroke rehabilitation: Evidence from the setting of an inpatient rehabilitation facility. Archives of Physical Medicine and Rehabilitation, 96, 14581466.Google Scholar
Cherney, L.R., Halper, A.S., Kwasnica, C.M., Harvey, R.L., & Zhang, M. (2001). Recovery of functional status after right hemisphere stroke: Relationship with unilateral neglect. Archives of Physical Medicine and Rehabilitation, 82, 322328.CrossRefGoogle ScholarPubMed
Coolican, H. (2009). Research methods and statistics in psychology. London, United Kingdom: Hodder Education.Google Scholar
Corbetta, M., & Shulman, L. (2011). Spatial neglect and attention networks. Annual Review of Neuroscience, 34, 569599.Google Scholar
Danckert, J., & Ferber, S. (2006). Revisiting unilateral neglect. Neuropsychologia, 44, 9871006.CrossRefGoogle ScholarPubMed
Di Monaco, M., Schintu, S., Dotta, M., Barba, S., Tappero, R., & Gindri, P. (2011). Severity of unilateral spatial neglect is an independent predictor of functional outcome after inpatient rehabilitation in individuals with right hemispheric stroke. Archives of Physical Medicine and Rehabilitation, 92, 12501256.Google Scholar
Erez, A.B.-H., Katz, N., Ring, H., & Soroker, N. (2009). Assessment of spatial neglect using computerised feature and conjunction visual search tasks. Neuropsychological Rehabilitation, 19, 677695.CrossRefGoogle ScholarPubMed
Farne, A., Buxbaum, L., Ferraro, M., Frassinetti, F., Whyte, J., Veramonti, T., & Làdavas, E. (2004). Patterns of spontaneous recovery of neglect and associated disorders in acute right brain-damaged patients. Journal of Neurology, Neurosurgery, and Psychiatry, 75, 14011410.Google Scholar
Folstein, M.F., Folstein, S.E., & McHugh, P.R. (1975). Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatry Research, 12, 189198.CrossRefGoogle Scholar
Friedrich, F.J., & Margolin, D.I. (1993). Responses time measures of hemi-inattention: A longitudinal case report. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 6, 5459.Google Scholar
Gainotti, G., De Luca, L., Figliozzi, F., & Doricchi, F. (2009). The influence of distracters, stimulus duration and hemianopia on first saccade in patients with unilateral neglect. Cortex, 45, 506516.CrossRefGoogle ScholarPubMed
Gainotti, G., D’Erme, P., & Bartolomeo, P. (1991). Early orientation of attention toward the half space ipsilateral to the lesion in patients with unilateral brain damage. Journal of Neurology, Neurosurgery, and Psychiatry, 54, 10821089.Google Scholar
Gerritsen, M.J.J., Berg, I.J., Deelman, B.G., Visser-Keizer, A.C., & Meyboom-de Jong, B. (2003). Speed of information processing after unilateral stroke. Journal of Clinical and Experimental Neuropsychology, 25, 113.CrossRefGoogle ScholarPubMed
Gillen, R., Tennen, H., & McKee, T. (2005). Unilateral spatial neglect: Relation to rehabilitation outcomes in patients with right hemisphere stroke. Archives of Physical Medicine and Rehabilitation, 86, 763767.CrossRefGoogle ScholarPubMed
Goldstein, L.B., Bertels, C., & Davis, J.N. (1989). Interrater reliability of the NIH stroke scale. Archives of Neurology, 46, 660662.CrossRefGoogle ScholarPubMed
Harvey, B.O.M., & Gilchrist, I.D. (2002). First Saccades reveal biases in recovered neglect. Neurocase, 8, 306313.Google Scholar
Heilman, K.M., Watson, R.T., & Valenstein, E. (1993). Neglect and related disorders. In K.M. Heilman & E. Valenstein (Eds.), Clinical neuropsychology (pp. 279336). New York: Oxford University Press.CrossRefGoogle Scholar
Husain, M., & Rorden, C. (2003). Non-spatially lateralized mechanisms in hemispatial neglect. Neuroscience, 4, 2636.Google ScholarPubMed
Jalas, M.J., Lindell, A.B., Brunila, T., Tenovuo, O., & Hämäläinen, H. (2002). Initial rightward orienting bias in clinical tasks: Normal subjects and right hemispheric stroke patients with and without neglect. Journal of Clinical and Experimental Neuropsychology, 24, 479490.Google Scholar
Jehkonen, M. (2002a). Behavioural Inattention Test. Manual. Helsinki: Psykologien Kustannus Oy. [In Finnish].Google Scholar
Jehkonen, M. (2002b). The role of visual neglect and anosognosias in functional recovery after right hemisphere stroke. (Doctoral dissertation, University of Tampere, Finland). Retrieved from http://acta.uta.fi/english/teos.php?id=6242 Google Scholar
Jehkonen, M., Laihosalo, M., Koivisto, A.-M., Dastidar, P., & Ahonen, J.P. (2007). Fluctuation in spontaneous recovery of left visual neglect: A 1-year follow-up. European Neurology, 58, 210214.Google Scholar
Karnath, H.O. (1988). Deficits of attention in acute and recovered visual hemi-neglect. Neuropsychologia, 261, 2743.Google Scholar
Karnath, H.-O., & Rorden, C. (2012). The anatomy of spatial neglect. Neuropsychologia, 50, 10101017.Google Scholar
Katz, N., Hartman-Maeir, A., Ring, H., & Soroker, N. (1999). Functional disability and rehabilitation outcome in right hemisphere damaged patients with and without unilateral spatial neglect. Archives of Physical Medicine and Rehabilitation, 80, 379384.Google Scholar
Kettunen, J.E., Nurmi, M., Dastidar, P., & Jehkonen, M. (2012). Recovery from visual neglect after right hemisphere stroke: Does Starting point in cancellation tasks change after 6 months? The Clinical Neuropsychologist, 26, 305320.Google Scholar
Lezak, M.D., Howieson, D.B., Bigler, E.D., & Tranel, D. (2012). Neuropsychological assessment (5th ed.). New York: Oxford University Press.Google Scholar
Mahoney, F.I., & Barthel, D.W. (1965). Functional evaluation: The Barthel index. Maryland State Medical Journal, 14, 6165.Google Scholar
Manly, T. (2002). Cognitive rehabilitation for unilateral neglect: Review. Neuropsychological Rehabilitation, 12, 289310.CrossRefGoogle Scholar
Manly, T., Dove, A., Blows, S., George, M., Noonan, M.P., Dodds, C.M., & Warburton, E. (2009). Assessment of unilateral spatial neglect: Scoring star cancellation performance from video recordings – Method, reliability, benefits, and normative data. Neuropsychology, 23, 519528.CrossRefGoogle ScholarPubMed
Mattingley, J.B., Bradshaw, J.L., Bradshaw, J.A., & Nettleton, N.C. (1994). Residual rightward attentional bias after apparent recovery from right hemisphere damage: Implications for a multicomponent model of neglect. Journal of Neurology, Neurosurgery, and Psychiatry, 57, 597604.CrossRefGoogle ScholarPubMed
Mesulam, M.M. (2000). Principles of behavioral and cognitive neurology (second edition). New York, NY: Oxford University Press.Google Scholar
Nurmi, L.J., Kettunen, J., Laihosalo, M., Ruuskanen, E.-I., Koivisto, A.-M., & Jehkonen, M. (2010). Right hemisphere infarct patients and healthy controls: Evaluation of starting points in cancellation tasks. Journal of the International Neuropsychological Society, 16, 902909.Google Scholar
Robertson, I.H. (1993). The relationship between lateralised and non-lateralised attentional deficits in unilateral neglect. In I.H. Robertson, and J.C. Marshall (Eds.), Unilateral Neglect: Clinical and experimental studies (pp. 257275). Hove, UK: Lawrence Erlbaum Associates.Google Scholar
Robertson, I.H. (2001). Do we need the “lateral” in unilateral neglect? Spatially nonselective attention deficits in unilateral neglect and their implications for rehabilitation. NeuroImage, 14, S85S90.Google Scholar
Robertson, L.C., & Eglin, M. (1993). Attentional search in unilateral visual neglect. In I.H. Robertson & J.C. Marshall (Eds.), Unilateral neglect: Clinical and experimental studies (pp. 169191). Hillsdale, NJ: Erlbaum.Google Scholar
Robertson, I.H., & Halligan, P.W. (1999). A clinical handbook for diagnosis and treatment. Hove, UK: Psychology Press.Google Scholar
Rorden, C., & Karnath, H.-O. (2010). A simple measure of neglect severity. Neuropsychologia, 48, 27582763.CrossRefGoogle ScholarPubMed
Samuelsson, H., Hjelmquist, E., Naver, H., & Blomstrand, C. (1996). Visuospatial neglect and an ipsilesional bias during the start of performance in conventional tests of neglect. The Clinical Neuropsychologist, 10, 1524.Google Scholar
Samuelsson, H., Hjelmquist, E.K.E., Jensen, C., Ekholm, S., & Blomstrand, C. (1998). Nonlateralized attentional deficits: An important component behind persisting visuospatial neglect? Journal of Clinical and Experimental Neuropsychology, 20, 7388.Google Scholar
Smania, N., Martini, M.C., Gambina, G., Tomelleri, G., Palamara, A., Natale, E., && Marzi, C.A. (1998). The spatial distribution of visual attention in hemineglect and extinction patients. Brain, 121, 17591770.Google Scholar
Suzuki, E., Chen, W., & Kondo, T. (1997). Measuring unilateral spatial neglect during stepping. Archives of Physical Medicine and Rehabilitation, 78, 173178.Google Scholar
Taylor, D. (2003). Measuring mild visual neglect: Do complex visual tests activate rightward attentional bias? New Zealand Journal of Physiotherapy, 31, 6772.Google Scholar
Ting, D.S.J., Pollock, A., Dutton, G.N., Doubal, F.N., Ting, D.S.W., Thompson, M., & Dhillon, B. (2011). Visual neglect following stroke: Current concepts and future focus. Survey of Ophthalmology, 56, 114133.Google Scholar
Tomczak, M., & Tomczak, E. (2014). The need to report effect size estimates revisited. An overview of some recommended measures of effect size. Trends in Sport Science, 1, 1925.Google Scholar
van Kessel, M.E., van Nes, I.J.W., Brouwer, W.H., Alexander, C.H., Geurts, A.C.H., & Fasotti, L. (2010). Visuospatial asymmetry and non-spatial attention in subacute stroke patients with and without neglect. Cortex, 46, 602612.Google Scholar
Viken, J. (2013). Visuospatial neglect and processing speed: Importance of lateralized and nonlateralized symptoms as predictors of functional outcome after stroke. (Doctoral dissertation, University of Gothenburg, Sweden). Retrieved from https://gupea.ub.gu.se/handle/2077/33882?locale=sv Google Scholar
Viken, J.I., Jood, K., Jern, C., Blomstrand, C., & Samuelsson, H. (2014). Ipsilesional bias and processing speed are important predictors of functional dependency in the neglect phenomenon after a right hemisphere stroke. The Clinical Neuropsychologist, 28, 974993.Google Scholar
Warren, M., Moore, J.M., & Vogtle, L.K. (2008). Search performance of healthy adults on cancellation tests. American Journal of Occupational Therapy, 62, 588594.Google Scholar
Webster, J.S., Roades, L.A., Morril, B., Rapport, L.J., Abadee, P.S., Sowa, M.V., & Godlewski, M.C. (1995). Rightward orienting bias, wheelchair manouvering, and fall risk. Archives of Physical Medicine and Rehabilitation, 76, 924928.Google Scholar
Wilson, B., Cockburn, J., & Halligan, P. (1987). Behavioural Inattention Test. Titchfield, UK: Thames Valley Test Company.Google Scholar
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