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The Effects of Smoking Cessation on the Risk Factors for the Metabolic Syndrome: A Follow-Up Study of Veterans

Published online by Cambridge University Press:  06 April 2016

Akbar Sharip ,
Anthony Firek  and
Serena Tonstad
Akbar Sharip*
Affiliation:
Department of Preventive Medicine, The Loma Linda University School of Medicine, Loma Linda, California 92354, USA
Anthony Firek
Affiliation:
Endocrinology Department, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, California 92354, USA
Serena Tonstad
Affiliation:
School of Public Health, The Loma Linda University, Loma Linda, California 92354, USA
*
Address for correspondence: Akbar Sharip, Department of Preventive Medicine Office, Loma Linda University, Evans Hall, Rm. 101 24785 Stewart Street Loma Linda, California 92350. Email: [email protected]
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Abstract

Objective: To evaluate the impact of short-term smoking cessation on Metabolic Syndrome (Mets) component risk factors, and hormones related to MetS and human metabolism.

Methods: Smoking veterans with MetS, attending stop smoking class, were followed up close to one year. Paired comparisons between after the follow up and baseline data were made using t-test.

Results: A total of 95 smoking veterans with MetS completed average close to one year follow up. Thirty subjects completely quit for the average of 6 months, while 36 subjects continued smoking during the follow up. At the end of study, quitters average waist circumference increased 2.98 cm (0.69–5.27), weight increased 2.05 kg (−0.03 to 4.13), HDL cholesterol increased 4.17 mg/dl (1.03–7.32), triglyceride decreased 56.17 mg/dl ((−1.96 to 111.20), and MetS prevalence decreased 13% (p = 0.05). The changes in ghrelin were moderately positively associated with duration of quitting smoking (R2 = 43.99, and p < 0.01).

Conclusion: Compared to the baseline, quitters HDL was up, triglyceride was down, and overall MetS prevalence was lower. The longer the duration of quitting, bigger the increase in ghrelin. There were no significant changes in serum leptin, ghrelin, serum insulin, and insulin resistance after quitting smoking.

Type
Original Articles
Information
Journal of Smoking Cessation , Volume 12 , Issue 3 , September 2017 , pp. 143 - 152
Copyright
Copyright © The Author(s) 2016 

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References

Ford, E., Li, C., & Sattar, N. (2008). Metabolic syndrome and incident diabetes: Current state of the evidence. Diabetes Care, 31 (9), 1898–904. doi: 10.2337/dc08-0423.CrossRefGoogle ScholarPubMed
Ishizaka, N., Ishizaka, Y., Toda, E., Hashimoto, H., Nagai, R., & Yamakado, M. (2005). Association between cigarette smoking, metabolic syndrome, and carotid arteriosclerosis in Japanese individuals. Atherosclerosis, 181, 381–388 Google Scholar
Kaur, J. (2014). A comprehensive review on metabolic syndrome. Cardiology and Research Practice, 2014, 943162.Google Scholar
Kim, B. J., Kim, B. S., Sung, K. C., Kang, J. H., Lee, M. H., & Park, J. R. (2009). Association of smoking status, weight change, and incident metabolic syndrome in men: A 3-year follow-up study. Diabetes Care, 32 (7), 1314–1316.Google Scholar
Lee, H., Joe, K., Kim, W., Park, J., Lee, D., Sung, K., & Kim, D. (2006). Increased leptin and decreased ghrelin level after smoking cessation. Neurosci Lett., 409 (1), 47–51.CrossRefGoogle ScholarPubMed
Messner, B., & Bernhard, D. (2014). Smoking and cardiovascular disease mechanisms of endothelial dysfunction and early Atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology, 34, 509–515.CrossRefGoogle ScholarPubMed
National Heart, Lung, and Blood Institute (2002). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Final Report. NIH Publication No. 02–5215. September 2002.Google Scholar
Slagter, S., van Vliet-Ostaptchouk, J., Vonk, J., Boezen, H., Dullart, R., Kobold, A. et al., (2013). Associations between smoking, components of metabolic syndrome and lipoprotein particle size. BMC Med., 11, 195. doi: 10.1186/1741-7015-11-195.CrossRefGoogle ScholarPubMed
Sun, K., Liu, J., & Ning, G. (2012). Active smoking and risk of metabolic syndrome: A meta-analysis of prospective studies. PLoS One, 7, e47791.CrossRefGoogle ScholarPubMed
Thomazin, G. (2008). Estimating the Prevalence of Metabolic syndrome Using VA Loma Linda EMR.Google Scholar
U.S. Department of Health and Human Services. (1990). The Health Benefits of Smoking Cessation. A Report of the Surgeon General. USDHHS, Centers for Disease Control. Office of Smoking and Health; 1990. DHHS Publication (CDC), 90–8416.Google Scholar
U.S. Department of Health and Human Services. (2014). The Health Consequences of Smoking—50 Years of Progress. A Report of the Surgeon General. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2014, Retrieved from http://www.surgeongeneral.gov/library/reports/50-years-of-progress/full-report.pdf.Google Scholar
Wada, T., Urashima, M., & Fukumoto, T. (2007). Risk of metabolic syndrome persists twenty years after the cessation of smoking. In- tern Med 2007, 46, 1079–1082.Google Scholar