Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-25T04:16:33.414Z Has data issue: false hasContentIssue false

Technical illustration of Volumetric arc conformal radiotherapy planning in a case of paratesticular sarcoma

Published online by Cambridge University Press:  18 January 2021

Anil Gupta
Affiliation:
Radiation Oncology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India
Rambha Pandey*
Affiliation:
All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi110029, India
Seema Sharma
Affiliation:
Radiation Oncology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India
Vivek Ghosh
Affiliation:
Radiation Oncology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India
Ekta Dhamija
Affiliation:
Radiodiagnosis, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India
Adarsh Barwad
Affiliation:
Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India
Sameer Rastogi
Affiliation:
Medical Oncology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India
Rishabh Kumar
Affiliation:
All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi110029, India
Rashi Kulshrestha
Affiliation:
British Columbia Cancer Agency, Radiation Oncology, 32900, Marshall Road, Abbotsford, British ColumbiaV2S 0C2, Canada
*
Author for correspondence: Rambha Pandey, Department of Radiation Oncology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi 110029, India. E-mail: [email protected]

Abstract

Introduction:

Paratesticular sarcoma are extremely rare malignant tumours. Unlike other sites, they tend to be lower grade and have higher propensity of lymphatic spread. They tend to fail locally and occasionally in the regional lymph nodes. In the absence of target volume delineation guidelines and technical illustration of conformal planning, we have made an attempt to illustrate conformal planning methodology and define target volume based on current evidence in a case of paratesticular sarcoma.

Methods:

We are presenting a case of 62-year-old male who presented with 15-cm scrotal swelling and underwent high inguinal orchidectomy with ligation of spermatic cord. Histopathology presented a well-differentiated leiomyosarcoma of epididymis. Post-operative radiotherapy target volume included the tumour bed, ipsilateral inguinal nodes and lower pelvic nodes as the clinical target volume.

Conclusion:

Adjuvant radiotherapy using advanced delivery technique such as volumetric arc technique can provide good dose distribution with good sparing of organs at risk. The downside of conformal radiation delivery is that it is a resource-intensive and has no established target volume delineation guidelines.

Type
Case Study
Copyright
© The Author(s), 2021. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bostwick, D G. Spermatic cord and testicular adnexa. In: Bostwick, D G, Cheng, L (eds). Urologic Surgical Pathology. 3rd edition. Philadelphia, PA, USA: Elsevier Saunders, 1997: 832. doi: 10.4065/72.2.188 Google Scholar
Clark, M A, Fisher, C, Judson, I, Meirion Thomas, J. Soft-Tissue sarcomas in adults. N Engl J Med 2005; 353 (7): 701711. doi: 10.1056/NEJMra041866 CrossRefGoogle ScholarPubMed
Stiller, C A, Trama, A, Serraino, D et al. Descriptive epidemiology of sarcomas in Europe: report from the RARECARE project. Eur J Cancer 2013; 49 (3): 684695. doi: 10.1016/j.ejca.2012.09.011 CrossRefGoogle ScholarPubMed
Rodríguez, D, Olumi, A F. Management of spermatic cord tumors: a rare urologic malignancy. Ther Adv Urol 2012; 4 (6): 325334. doi: 10.1177/1756287212447839 CrossRefGoogle ScholarPubMed
Khoubehi, B, Mishra, V, Ali, M, Motiwala, H, Karim, O. Adult paratesticular tumours. BJU Int 2002; 90 (7): 707715. doi: 10.1046/j.1464-410x.2002.02992.x CrossRefGoogle ScholarPubMed
Gandhi, A K, Sharma, D N, Rath, G K et al. Early clinical outcomes and toxicity of intensity modulated versus conventional pelvic radiation therapy for locally advanced cervix carcinoma: a prospective randomized study. Int J Radiat Oncol Biol Phys 2013; 87 (3): 542548. doi: 10.1016/j.ijrobp.2013.06.2059 CrossRefGoogle ScholarPubMed
Cerda, T, Martin, É, Truc, G, Créhange, G, Maingon, P. Safety and efficacy of intensity-modulated radiotherapy in the management of spermatic cord sarcoma. Cancer Radiother 2017; 21 (1): 1620. doi: 10.1016/j.canrad.2016.07.102 CrossRefGoogle ScholarPubMed
Taylor, A, Rockall, A G, Reznek, R H, Powell, M E B. Mapping pelvic lymph nodes: guidelines for delineation in intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2005; 63 (5): 16041612. doi: 10.1016/j.ijrobp.2005.05.062 CrossRefGoogle ScholarPubMed
Bansal, A, Patel, F, Rai, B, Gulia, A, Dhanireddy, B, Sharma, S. Literature review with PGI guidelines for delineation of clinical target volume for intact carcinoma cervix. J Cancer Res Ther 2013; 9 (4): 574582. doi: 10.4103/0973-1482.126450 Google ScholarPubMed
Kim, C H, Olson, A C, Kim, H, Beriwal, S. Contouring inguinal and femoral nodes; how much margin is needed around the vessels? Pract Radiat Oncol 2012; 2 (4): 274278. doi: 10.1016/j.prro.2011.12.005 CrossRefGoogle ScholarPubMed
Menzel, H G. The international commission on radiation units and measurements. J ICRU 2010; 10 (1): 1106. doi: 10.1093/jicru/ndq001 Google Scholar
Tiong, S S, Dickie, C, Haas, R L, O’Sullivan, B. The role of radiotherapy in the management of localized soft tissue sarcomas. Cancer Biol Med 2016; 13 (3): 373383. doi: 10.20892/j.issn.2095-3941.2016.0028 CrossRefGoogle ScholarPubMed
Catton, C, Jewett, M, O’Sullivan, B, Kandel, R. Paratesticular sarcoma: failure patterns after definitive local therapy. J Urol 1999; 161 (6): 18441847. doi: 10.1016/s0022-5347(05)68823-4 CrossRefGoogle ScholarPubMed
Bozzini, G, Albersen, M, Romero Otero, J et al. Feasibility and safety of conservative surgery for the treatment of spermatic cord leiomyosarcoma. Int J Surg 2015; 24 (Pt A): 8184. doi: 10.1016/j.ijsu.2015.11.012 CrossRefGoogle ScholarPubMed
Enoch, S, Wharton, S M, Murray, D S. Management of leiomyosarcomas of the spermatic cord: the role of reconstructive surgery. World J Surg Oncol 2005; 3 (23): 17. doi: 10.1186/1477-7819-3-23 CrossRefGoogle ScholarPubMed
Rodríguez, D, Barrisford, G W, Sanchez, A, Preston, M A, Kreydin, E I, Olumi, A F. Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes. Urol Oncol 2014; 32 (1): 52.e19–25. doi: 10.1016/j.urolonc.2013.08.009 CrossRefGoogle ScholarPubMed