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Calypso® 4D Localization System: a review

Published online by Cambridge University Press:  05 August 2014

C. Silva ,
D. Mateus ,
M. Eiras  and
S. Vieira
C. Silva*
Affiliation:
Escola Superior de Tecnologias da Saúde de Lisboa, Portugal Centro Clínico Fundação Champalimaud, Lisboa, Portugal
D. Mateus
Affiliation:
Centro Clínico Fundação Champalimaud, Lisboa, Portugal
M. Eiras
Affiliation:
Escola Superior de Tecnologias da Saúde de Lisboa, Portugal
S. Vieira
Affiliation:
Centro Clínico Fundação Champalimaud, Lisboa, Portugal
*
Correspondence to: Célia Silva, R. Outeiro Cacho, 6, Loureira, 2495-161 Sta Cat Serra, Portugal. Tel: 00351919628745. E-mail: [email protected]
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Abstract

Purpose

Calypso® 4D Localization System is a system based on electromagnetic transponders detection enabling precise 3D localisation and continuous tracking of tumour target. This review intended to provide information in order to (1) show how Calypso® 4D Localization System works, (2) to present advantages and disadvantages of this system, (3) to gather information from several clinical studies and, finally, (4) to refer Calypso® System as a tool in dynamic multileaf collimator studies for target motion compensation.

Methods

A structured search was carried out on B-On platform. The key words used in this research were ‘Calypso’, ‘Transponder’, ‘Electromagnetic Localization’, ‘Electromagnetic Tracking’, ‘Target Localization’, ‘Intrafraction Motion’ and ‘DMLC’.

Review

Treatment the implanted transponders are excited by an electromagnetic field and resonate back. These frequencies are detected and Calypso® software calculates the position of the transponders. If the movement detected is larger than the limits previously defined, irradiation can be stopped. The system has been proven to be submillimetre accurate.

Discussion

Calypso® System has been presented as an accurate tool in prostate radiotherapy treatments. The application of this system to other clinical sites is being developed.

Conclusion

The Calypso® System allows real-time localisation and monitoring of the target, without additional ionising radiation administration. It has been a very useful tool in prostate cancer treatment.

Keywords

Beacon® transpondersCalypso®DMLClungprostate
Type
Literature Reviews
Information
Journal of Radiotherapy in Practice , Volume 13 , Issue 4 , December 2014 , pp. 473 - 483
Copyright
© Cambridge University Press 2014 

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