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A dosimetric comparison of linac-based stereotactic fractionated radiotherapy techniques for pituitary adenoma and craniopharyngioma

Published online by Cambridge University Press:  20 February 2018

Sunitha S. Varghese ,
Giriyappa Goudar ,
Susen Abraham ,
Timothy Peace ,
Rabi R. Singh  and
Sevamani Backianathan
Sunitha S. Varghese*
Affiliation:
Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
Giriyappa Goudar
Affiliation:
Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
Susen Abraham
Affiliation:
Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
Timothy Peace
Affiliation:
Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
Rabi R. Singh
Affiliation:
Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
Sevamani Backianathan
Affiliation:
Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
*
Author for correspondence: Sunitha Susan Varghese, Christian Medical College and Hospital Vellore, Vellore 632004, Tamil Nadu, India. Tel: 91 416 228 3145. E-mail: [email protected]
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Abstract

Aim

To compare the dosimetric outcomes of linear accelerator-based stereotactic radiotherapy (SRT) techniques—static conformal field (SCF), static conformal arc (SCA) and dynamic conformal arc (DCA), for treating pituitary adenoma and craniopharyngioma.

Materials and methods

Computer image sets of 20 patients with pituitary adenoma or craniopharyngioma and treated with post-operative SRT were selected for this study. For each dataset, three SRT plans, with SCF, SCA and DCA techniques were generated using Brain LAB, iPlan RT V.4.5.3, TPS software. The conformity index (CI), homogeneity index (HI), quality of coverage of the target, dose–volume histograms for the target and organs at risk (OARs) and the time taken to deliver treatment was compared across three sets of plan.

Results

There were 12 patients with pituitary adenoma and eight with craniopharyngioma. The CI and HI were comparable across three techniques. The quality of coverage was superior in DCA technique. OARs were better spared in SCF and DCA techniques. Time taken to deliver treatment was least in SCF technique.

Conclusions

The linac-based SRT techniques SCF, SCA and DCA are efficient in delivering highly conformal and homogenous dose to the target in pituitary adenoma and craniopharyngioma. Among these three techniques, SCF and DCA had acceptable quality of coverage. The dose received by OARs was least in the SCF technique.

Keywords

craniopharyngiomapituitary adenomastereotactic radiotherapy
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 17 , Issue 3 , September 2018 , pp. 313 - 318
Copyright
© Cambridge University Press 2018 

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