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Dosimetric comparison of helical tomotherapy and hybrid (3DCRT-VMAT) technique for locally advanced non-small cell lung cancer

Published online by Cambridge University Press:  22 May 2020

Öztun Temelli Open the ORCID record for Öztun Temelli [Opens in a new window] ,
Mehmet Demirtas Open the ORCID record for Mehmet Demirtas [Opens in a new window]  and
Berat Tugrul Ugurlu Open the ORCID record for Berat Tugrul Ugurlu [Opens in a new window]
Öztun Temelli*
Affiliation:
Inonu University, Malatya, Turkey
Mehmet Demirtas
Affiliation:
Inonu University, Malatya, Turkey
Berat Tugrul Ugurlu
Affiliation:
Inonu University, Malatya, Turkey
*
Author for correspondence: Öztun Temelli, E-mail: [email protected]
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Abstract

Aim:

The purpose of the present study is to compare hybrid [three-dimensional conformal radiation therapy-volumetric-modulated arc therapy (3DCRT-VMAT)] and helical tomotherapy (HT) techniques in terms of both planning target volume (PTV) and organs at risk (OARs) in the plans we made in locally advanced non-small cell lung cancer (NSCLC) patients

Material and methods:

Radiotherapy was planned for 15 locally advanced NSCLC patients with 2 different techniques. Large tumours with positive mediastinal lymph nodes were preferred. The prescription dose was determined as 60 Gy at 30 fractions.

Results:

Mean PTV volume was 602·5 cc (range: 265–1461). Mean total lung volume was 4264 cc (range: 1885–6803). Homogeneity index, Dmean, Dmax, D2 and V105 were found to be lower in HT, V100, total monitor units (MU) and total beam on time were found to be lower in the hybrid plan. Total lung Dmean was found to be 17 Gy in both techniques. V10 value was 42·85 in the hybrid plan and 48·67 in HT (p = 0·037). Heart Dmean was 14·5 Gy in the hybrid plan and 18·7 in HT (p < 0·001), and V30 values were 18·1 and 22·9, respectively (p = 0·009).

Conclusion:

Suitable dose coverage and OAR doses can be provided with both techniques. Especially the opposite lung, heart and oesophagus doses can be kept lower with the hybrid plan, and lower MU and shorter beam on time can be provided.

Keywords

lung cancerhybrid techniquehelical tomotherapydosimetric comparison
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 20 , Issue 3 , September 2021 , pp. 300 - 305
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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