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Tuberose Sclerosis Treated by Deep Irradiation

Published online by Cambridge University Press:  08 February 2018

Brian H. Kirman
Brian H. Kirman*
Affiliation:
From The Fountain Hospital, Tooting, London
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Extract

Epiloia occupies an intermediate position between the neoplasms on the one hand and other diseases, such as Huntington's chorea and Tay-Sachs disease, which are system disturbances, presumably based on a metabolic disorder. The lesions in the disease-complex of epiloia might at first sight appear mainly neoplastic in form. Thus the brain nodules have the form of gliomata. Polycystic kidneys may be classed as neoplastic (Jeanbrau, 1928; Vines, 1949). In some cases a frank hypernephroma may develop (Kirpicznik, 1910; Berg, 1913; Ferraro and Doolittle, 1937). The rarely encountered heart lesions may take the form of rhabdomyomata, whereas the skin lesions of the face which are pathognomonic of the disease are described as sebaceous adenomata (Figs. 1 and 2), i.e. benign neoplasms of the sebaceous glands of the face in the area to either side of the nose. In fact the facial eruption is seldom simply adenomatous but is complicated by elements of an angiomatous or warty nature. The heart lesion may likewise involve a variety of elements.

Type
Original Articles
Information
Journal of Mental Science , Volume 100 , Issue 420 , July 1954 , pp. 711 - 717
Copyright
Copyright © Royal College of Psychiatrists, 1954 

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