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A Trial of Tetrabenazine (‘Nitoman’) in Disturbed Mentally Subnormal Patients

Published online by Cambridge University Press:  08 February 2018

G. C. Kanjilal  and
B. Matheson
G. C. Kanjilal
Affiliation:
Stallington Hall Hospital, Blythe Bridge, Stoke-on-Trent; formerly Senior Medical Officer, South Ockendon Hospital
B. Matheson
Affiliation:
South Ockendon Hospital, Essex
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Extract

In this country reserpine is not used extensively as a tranquillizer for disturbed mentally subnormal patients, and a phenothiazine is usually the first drug of choice. This is probably due to the undesirable side-effects of reserpine, of which lethargy, depression, hypotension and Parkinsonism are the most important. However, a number of hyperactive and disturbed patients have in our experience responded better to reserpine than to a phenothiazine. Consequently, when a compound said to have an essentially similar action but to be free of these side-effects became available, we felt that a clinical evaluation should be undertaken.

Type
Therapeutic Trials
Information
Journal of Mental Science , Volume 108 , Issue 453 , March 1962 , pp. 225 - 228
Copyright
Copyright © Royal College of Psychiatrists, 1962 

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References

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