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The Significance of Acidosis in Certain Nervous Disorders

Published online by Cambridge University Press:  19 February 2018

B. H. Shaw
B. H. Shaw*
Affiliation:
County Mental Hospital, Stafford
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Extract

The clinical evidence of acidosis is the detection of acetone bodies in the urine. Acetone is formed from diacetic acid by the splitting off of carbonic acid, the origin of diacetic acid being in part from fats and in part from proteins. Oxybutyric acid is also formed from diacetic acid by reduction, consequently the presence of acetone bodies in the urine always means that acidosis is taking place. A delicate test is that known as Rothera's, which is quite simple, and will detect acetone in minute dilution:

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 66 , Issue 274 , July 1920 , pp. 244 - 254
Copyright
Copyright © Royal College of Psychiatrists, 1920 

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