The details of the case I now propose to speak of have been published in the January and July numbers of “The Journal of Mental Science” of this year. In the January number the clinical history was reported as far as it went; shortly after its publication the patient died, and in the July issue the further progress and termination of the case were given, and the result of the post-mortem examinations detailed. I will not now detain you by reading the full report, but in order to carry you with me it will be necessary to recapitulate the main features of the case, supplementing them by a few particulars which have been evolved by further study of the pathological appearances presented in microscopic sections.