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The Relative Efficacy of “Vespral” and Chlorpromazine in the Treatment of a Group of Chronic Schizophrenic Patients

Published online by Cambridge University Press:  08 February 2018

G. P. Walsh ,
D. Walton  and
D. A. Black
G. P. Walsh
Affiliation:
Rainhill Hospital
D. Walton
Affiliation:
Rainhill Hospital and Winwick Hospital
D. A. Black
Affiliation:
Rainhill Hospital
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Extract

Vespral, or triflupromazine Squibb, is a new phenothiazine derivative. Chemically the compound is 10-(3-dimethylaminopropyl)-2-(trifluoro methyl) phenothiazine hydrochloride. Its structural formula compares with that of chlorpromazine as follows:

Until recently “Vespral” has been available in this country only for clinical trials, but its supposed therapeutic effects have been investigated fairly extensively in the United States and Canada (Goldman; Gallagher and Pfeiffer; Niswander, Lind and Schlesinger; Freed; Azima; Pennington; Saunders; Freyhan; Cahn and Levy).

Type
Original Articles
Information
Journal of Mental Science , Volume 105 , Issue 438 , January 1959 , pp. 199 - 209
Copyright
Copyright © Royal College of Psychiatrists, 1959 

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