It is currently admitted that the state of intoxication in neuropathic persons differs from that of normal individuals or of habitual drunkards. Of this peculiar state Bonhoeffer has lately given an excellent account, but when one attempts to gain a clear conception of it the clinical cases scarcely bear out the general description. It will, therefore, perhaps be not inappropriate to go over some cases of this pathological form of intoxication which are not yet numerous and endeavour to gather them into a more definite group.