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Phenytoin Toxicity with Associated Meningeal Reaction

Published online by Cambridge University Press:  08 February 2018

Peter Dutton
Peter Dutton*
Affiliation:
Burnley Group of Hospitals
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Extract

Phenytoin Sodium (Sodium diphenylhydantoinate) is established in the treatment of epilepsy. Toxic side effects, especially on the nervous system, have been well documented. Untoward reactions may follow therapeutic doses taken over a period of time, or as the result of a single massive dose taken accidentally or with suicidal intent.

The following case of toxic reaction is reported because of the unusual mode of presentation and the associated C.S.F. changes.

Type
Original Articles
Information
Journal of Mental Science , Volume 104 , Issue 437 , October 1958 , pp. 1165 - 1166
Copyright
Copyright © Royal College of Psychiatrists, 1958 

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References

Williamson, , J. Ment. Sci., Sept., 1940, 981.Google Scholar
Graveleau, J., Leveau, J., and Morin, M., Semaine des Hôpitaux de Paris, Sept. 2nd, 1954, 3367.Google Scholar
Airing, and Rosenbaum, , Arch. Neur. Psych, 1941, 45, 265.CrossRefGoogle Scholar
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