After noting the importance not merely of the study of the origin, evolution, and structure of the central nervous system, but the importance of the attempt to correlate these with the actual life-activities of the organism in both health and disease, Dr. Andriezen showed how the neglect of alienists to follow and work up these investigations entailed their falling back and separation from the advancing army of neurological workers. He hoped that, with the awakening of the spirit of inquiry and scientific research in our asylums, that reproach might be wiped away, and that an attempt would be made to study and localize the lesions in the insanities, making use of all the methods available—neurological, psychological, pathological, sociological, and experimental.