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The Occurrence and Significance of Small Vascular Lesions in the Brain

Published online by Cambridge University Press:  08 February 2018

F. A. Pickworth
F. A. Pickworth*
Affiliation:
Department of Mental Disease Research, University of Birmingham
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Extract

The haemorespiratory system is subject to disease like any other tissue of the body. Degenerative changes of large arteries are known to have occurred thousands of years ago, and atherosclerosis is to be found throughout the world irrespective of race or geographical distribution. The first recorded observations of disease of the cerebral vessels appeared in the year 1700 (1). Perivascular softenings were noted in 1814 (2); a book on disease of the brain with clinical associations was published in 1836 (3). Atheroma was studied in 1844 (4), and periarteritis of the cerebral vessels in 1868 (5) and 1887 (6). Changes in the vessel walls and perivascular cells were noted in 1863 (7), and white cells and emboli seen in cerebral vessels in 1882 (8).

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 87 , Issue 366 , January 1941 , pp. 50 - 76
Copyright
Copyright © Royal College of Psychiatrists, 1941 

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References

1 Brunner q. (1932), this Journal (July).Google Scholar
2 Rochoux q. (1932), this Journal (July).Google Scholar
3 Abercrombie, J. (1836), Diseases of the Brain. Google Scholar
4 Rokitansky, C. (1844) Handbook of Anatomy. Google Scholar
5 Charcot, and Bouchard, (1868), Arch. de Phys., 1, 643.Google Scholar
6 Eppinger, (1887), Arch. f. klin. Chir. Berlin, 2, 719.Google Scholar
7 Rindfleisch, , q. Dawson (1916), Rev. Neuro-Psych., 14, 285.Google Scholar
8 Ribbert, , q. Dawson (1916), ibid., 14, 285.Google Scholar
9 Davidson, G. (1934), Medical Record (December 5).Google Scholar
10 Pickworth, F. A. (1937), this Journal (September).Google Scholar
11 Idem (1929), Mott Memorial Volume. Google Scholar
12 Gerard, R. W. (1937), A.R.N.M.D, 18, 316.Google Scholar
13 Ford, F. R., Diseases of the Nervous System. Google Scholar
14 Clark, E. R., and Clark, E.L. (1939), Amer. Journ. Anat., 251.Google Scholar
15 Clark, W. E. le Gros, The Tissues of the Body. Google Scholar
16 Rous, and Gilding, (1930), Journ. Exp. Med., 51, 27.Google Scholar
17 Cowdry, E. (1939), The Problems of Ageing. Google Scholar
18 Hertzman, and Francke, (1935), Amer. Journ. Physiol., 113, 63.Google Scholar
19 Rous, Gilding and Smith, (1930), Journ. Exp. Med., 51, 807.Google Scholar
20 Moon, V. (1938), Shock and Related Capillary Phenomena. Google Scholar
21 Rous, and Gilding, (1929), Journ. Exp. Med., 50, 189, 489.CrossRefGoogle Scholar
22 Mallory, (1935), Journ. Nerv. and Ment. Dis. Google Scholar
23 Fisher, A. (1913-14), Amer. Journ. Physiol., 48, 37.Google Scholar
24 Clark, E. (1932), Amer. Journ. Anat., 49, 441.Google Scholar
25 Wilson, H. (1936), Journ. Pharm. Exp. Ther., 56, 446.Google Scholar
26 Best, and Taylor, (1937), Physiological Basis of Medical Practice. Google Scholar
27 Pickworth, F. A. (1938), Brit. Med. Journ., i, 265.Google Scholar
28 Clark, W. E. le Gros (1940), Journ. Anat., 74, 471.Google Scholar
29 McDowall, R. (1938), The Control of the Circulation of the Blood. Google Scholar
30 Schmidt, C. F. (1938), A.R.N.M.D., 18.Google Scholar
31 Cohnheim, (1867), q. Vejlens (32).Google Scholar
32 Vejlens, G. (1938), Act. Path. Scand., supp., 33.Google Scholar
33 Swindle, P. (1937), Amer. Journ. Physiol., 120, 58.CrossRefGoogle Scholar
34 Friedman, and Elkeles, (1934), Lancet, i, 719.Google Scholar
35 Cowdry, and Nicholson, (1924), Journ. Exp. Med., 827.Google Scholar
36 Semerak, C. B. (1921), Journ. Infect. Dis., 29, 190.CrossRefGoogle Scholar
37 Dickson, (1920), Medical Abstracts, 2, 470.Google Scholar
38 Putnam, T. (1935), Internat. Neurol. Congress. Google Scholar
39 Winklemann, N. (1933), Amer. Journ. Psychiat., 12, 775.Google Scholar
40 Hassin, G. (1933), Histopathology of the Peripheral and Central Nervous Systems. CrossRefGoogle Scholar
41 Lawen, and Paulus, , q. Franklin (1937), A Monograph on Veins Google Scholar
42 Banks, and Evans, (1918), Journ. R.A.M.C., 30.Google Scholar
43 MacAdam, (1916), ibid., 27.Google Scholar
44 Adami, , q. Pickworth (1928), this Journal (October).Google Scholar
45 Desgorges, , q. Pickworth (1928), this Journal (October).Google Scholar
46 Mott, F. W. (1907), Arch. Neurol., 3, 281.Google Scholar
47 Hedron, (1912), Nordiskt. Med. Ark., 20, 3.Google Scholar
48 Ellis, A. G. (1909), Proc. Path. Soc. Philadelphia, 12, 197.Google Scholar
49 Dobbs, and de Saram, (1938), Journ. Path. Bact., 46, 437.Google Scholar
50 Goldscheider, , q. Vejlens (32).Google Scholar
51 Gordon, A. (1928), Zeits. f. Neur. u. Psych., 19.Google Scholar
52 Stopford, J. (1918), Lancet, i, 465.Google Scholar
53 Todd, E. (1913), Journ. Anat. and Physiol. Google Scholar
54 Ferraro, A. (1929), Arch. Neur. Psych., 21, 69 (January).Google Scholar
55 de Vries, E. (1931), ibid., 25, 227.Google Scholar
56 Manwaring, W. H. (1923), Journ. Immunol., 8, 83.Google Scholar
57 Winkleman, N. (1931), Amer. Journ. Psych., 10, 611.Google Scholar
58 Duret, H. (1920), Traumatisms Cranio Cerebraux. Google Scholar
59 Pines, N. (1939), Brit. Med. Journ., 583.Google Scholar
60 Wolfe, T. (1930), Journ. Exp. Med., 51, 563.Google Scholar
61 Pickworth, F. A. (1934), this Journal (January).Google Scholar
62 Osler, W. (1917), Lancet, i, 1789.Google Scholar
63 Pickworth, F. A. (1934), Journ. Anat., 69, 62.Google Scholar
64 Annual Report Joint Bd. of Research, Birmingham, 1937-8.Google Scholar
65 Pickworth, F. A. (1935), Nasal Sinusitis and Mental Disorder. Google Scholar
66 Maitland, and Beling, (1929), Arch. Neur. Psych., 22, 1001.Google Scholar
67 Shaw, A. B. (1926), Journ. Path. and Bact., 29, 389.Google Scholar
68 Barron, and Chambers, (1935-6), Amer. Journ. Physiol., 114, 77 and 700.Google Scholar
69 Graff, S. (1921), Berl. klin. Woch., 58, 84.Google Scholar
70 Kubie, L. (1927), Journ. Exp. Med., 46, 615.CrossRefGoogle Scholar
71 Lowenberg, K. (1928), Arch. Neur. Psych., 19, 638.CrossRefGoogle Scholar
72q. Globus, J. (1932), A.R.N.M.D., 44.Google Scholar
73 Weil, A. (1930), Arch. Path., 9, 828.Google Scholar
74 Neuberger, , q. de Vries (55).Google Scholar
75 Chung, M. F. (1926), Arch. Derm. and Syph. (August).Google Scholar
76 Cobb, S. (1931), Arch. Neur. Psych., 25.Google Scholar
77 Orr, and Rows, (1917), Brain, 11, 1.Google Scholar
78 Hadfield, and Garrod, , R. A. Path., 3rd ed. Google Scholar
79 Okell, and Elliott, (1935), Lancet, ii, 869.Google Scholar
80 Round, Kirkpatrick and Hails, (1936), Proc. Roy. Soc. Med., 29.Google Scholar
81 Alexander, L., and Campbell, C. (1937), Amer. Journ. Path., 1, 229.Google Scholar
82 Dunn, J. (1921). Journ. Path. and Bact., 24, 118.Google Scholar
83 Gildea, and Cobb, (1930), Arch. Neur. Psych., 23, 901.Google Scholar
84 Olkon, D. (1930), Journ. Nerv. and Ment. Dis., 72, 538.CrossRefGoogle Scholar
85 Ruuman, (1929), q. Krogh, Anat. Physiol. of Capill. Google Scholar
86 Pickworth, F. A. (1925), this Journal (October).Google Scholar
87 Frazer, P. (1936), Journ. Laryngol. Otol., 51, 579.Google Scholar
88 Fuchs, O. (1921), Wiener med. Woch., 71, 710.Google Scholar
89 Davison, C., and Kelman, H. (1939), Arch. Neur. Psych., 42, 595.Google Scholar
90 Hawes, R. (1930), Brit. Med. Journ., 728 (November).Google Scholar
91q. Fitzgerald, (1934), Brit. Journ. Vener. Dis. (April).Google Scholar
92 Oseki, (1924), Arb. d. Neur. Inst. Wien., 26, 157.Google Scholar
93 Hollander, B. (1929), Bull. d'Acad. Roy. de Méd. Belgique, 524.Google Scholar
94 Olkon, D. (1939), Arch. Neur. Psych., 652.Google Scholar
95 Penfield, et al. (1939), Journ. Neurophysiol., 2, 257.CrossRefGoogle Scholar
96 Trotter, W. (1914), Choyce, System of Surgery, 3, 357.Google Scholar
97 Craigie, (1928), q. Fulton, Brain, 51, 310.Google Scholar
98 Hindze, (1935), q. Acta Psych. at Scand., Supp., 6.Google Scholar
99 Gruber, and Roberts, (1926), Journ. Pharm. Exp. Ther., 28, 327.Google Scholar
100 Roemer, and Jacobi, (1911), Arch. Exp. Path. u. Pharm., 66, 241.Google Scholar
101 Pickworth, F. A. (1927), Proc. Roy. Soc. Med., 20, 39.Google Scholar
102 Pollock, and Davis, , q. Fulton, J. F., Physiology of Nervous System, p. 153.Google Scholar
103 Cannon, W. B. (1927), Amer. Journ. Psychiat., 39, 106.Google Scholar
104 Penfield, W. (1938), Arch. Neur. Psych., 40, 417.Google Scholar
105 Collens, and Willensky, (1939), Peripheral Vascular Disease. Google Scholar
106 Elsberg, and Stookey, (1923), Arch. Neur. Psych., 9, 613.Google Scholar
107 Sugar, O., and Gerard, R. W. (1938), Journ. Neurophysiol., 1, 558.Google Scholar
108 Himwich, et al. (1939), Amer. Journ. Physiol., 125, 578.Google Scholar
109 Gerard, R. W., and Serota, H. (1936), Proc. Amer. Phys. Soc., 116, 59.Google Scholar
110 Robson, J., and Schild, H. (1938), Journ. Physiol., 92, 9.CrossRefGoogle Scholar
111 Roizin, L. (1939), Riv. Patol. Nerv. Ment., 53, 491.Google Scholar
112q. Hassin, G. (1929), Arch. Neur. Psych., 22, 375.CrossRefGoogle Scholar
113 Haldane, J. S. (1922), Respiration. Google Scholar
114 Hill, (1898) and Martius (1905), q. McDowall (29).Google Scholar
115 Stary, and Collins, (1930), q. McDowall (29).Google Scholar
116 Hildebrandt, (1831), q. McDowall (29).Google Scholar
117 Liddell, and Carleton, , q. McDowall (29).Google Scholar
118 Santha, and Cipriani, , q. Penfield, (1939), Journ. Neurophysiol., 2, 257.Google Scholar
119 Coghill, (1939), Anatomy of Behaviour. Google Scholar
120 Penfield, W. (1938), A.R.N.M.D., 18, 363.Google Scholar
121 Cobb, S., and Talbot, (1927), Tr. Amer. Physic., 42, 255.Google Scholar
122 Alexander, F. (1912), Bioch. Ztsch., 44, 127.Google Scholar
123 Fulton, J. F. (1928), Brain, 51, 310.Google Scholar
124 Santha, and Cipriani, (1938), A.R.N.M.D., 18, 346.Google Scholar
125 Schmidt, C. F. (1938), ibid., 18, 229.Google Scholar
126 Myerson, (1939), ibid., 19.Google Scholar
127 Speransky, (1938), Life, p. 28 (September 26).Google Scholar
128 Shellshear, J. C. (1927), Brain, 50, 236.Google Scholar
129 Robinson, G. (1927), Journ. Neur. Psych., 7, 332.Google Scholar
130 Duke, R. S. (1927), Journ. Tenessa., 19, 213.Google Scholar
131 Head, H. (1901), Brain, 24, 1.Google Scholar
132 Hirsch, et al. (1927), Journ. Amer. Med. Assoc., 89, 516.Google Scholar
133 Royle, N. D. (1932), Brit. Med. Journ., i, 1063.Google Scholar
134 Graves, T. C. (1932), this Journal, 78, 459.Google Scholar
135 Bryant, (1906), Journ. Nerv. Ment. Dis. Google Scholar
136 Spielmeyer, (1937), q. discussion, this Journal, 83, 532.Google Scholar
137 Pfeiffer, R. (1935), Kreislauf und Hirntuberkulose. Google Scholar
138 Scholtz, W. (1938), Zf. Neur. u. Psych., 163, 192.Google Scholar
139 Merritt, Putnam and Campbell, (1937), Arch. Neur. Psych., 37, 75.Google Scholar
140 Ferraro, and Jervis, (1936), ibid., 36, 739.Google Scholar
141 Bailey, P., q. Fulton, Physiol. of the Nervous System, p. 259.Google Scholar
142 Graves, T. C., unpublished.Google Scholar
143 Freeman, W. (1933), Neuropathology. Google Scholar
144 Grant, and Kirkland, (1927), this Journal, 73, 595.Google Scholar
145 Armstrong Jones, R. (1924), in Pierce, , “Addresses to Mental Nurses.”Google Scholar
146 Braunmuhl, von (1928), Zt. f. ges. Neur. u. Psych., 117, 163.Google Scholar
147 Briscoe, G. (1926-27), Journ. Physiol., 61, 353.Google Scholar
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