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Observations on the use of Tridione in Disturbed Psychotics

Published online by Cambridge University Press:  08 February 2018

E. P. Hall
E. P. Hall*
Affiliation:
Netherne Hospital, Coulsdon, Surrey
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Extract

Tridione (Abbott) is 3.5.5-Trimethyloxazolidine-2, 4-dione, and has been demonstrated clinically to have an inhibitory effect on petit mal, myoclonic and psychomotor seizures in epilepsy. Gibbs, Gibbs and Lennox first demonstrated a similarity between the cortical dysrhythmias in certain cases of schizophrenia and those of psychomotor epilepsy, whilst Kalinowsky and Putnam, as a result of these findings, gave the anti-convulsant dilantin as a successful sedative to 60 cases showing mental symptoms. Since tridione has a specific action against psychic equivalents in epilepsy, it was thought that its administration to patients showing chronic mental disturbances might result in at least a similar improvement.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 94 , Issue 397 , October 1948 , pp. 733 - 736
Copyright
Copyright © Royal College of Psychiatrists, 1948 

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References

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